A booked out BioRN Lounge welcomed Prof. Andreas Trumpp from Hi-STEM
BioRN Lounge Prof. Andreas Trumpp from HI-STEM talked about “Stem Cells and Cancer: From Molecular Mechanism to Clinical Trials”
Once again, the BioRN Lounge was the occasion for the life science companies as well for scientists from our research institutes, to meet and chat about latest news and achievements. The BioRN Lounge is the prime monthly networking event for BioRN members. It is the occasion for exchange, meeting and interaction in a very relaxed atmosphere with some drinks and food.
In addition, an invited speaker from the network presents and discusses with the participants, scientific trends, outbreaking techniques, outstanding research and more. Yesterday the Lounge event was completely booked to welcome Prof. Andreas Trumpp. He is Managing Director of HI-STEM gGmbH, Head Division of Stem Cells and Cancer at the German Cancer Research Center (DKFZ) and Co-Director DKFZ-ZMBH Alliance.
HI-STEM is a cutting-edge research institution bridging basic research (i.e. DKFZ) with patients outreach and clinical approaches (i.e. National Centre for Tumour Diseases-NCT, University Hospitals in Heidelberg and in Mannheim).
Prof. Trumpp provided to the audience an extended overview on stem cells and their role in health and cancer. In healthy conditions, stem cells have two main roles: tissue regeneration and tissue repair.
“Stem cells are responsible for example for the regeneration of the skin. Especially on the face, the skin is replaced completely in around 6-8 weeks. Therefore -every 6 weeks- by standing in front of the mirror, we can look to a completely new face”
Mutations at stem cells level can lead to tumours. Prof. Trumpp reported different studies on various cancer types (i.e. leukaemia, breast cancer, pancreatic cancer), and was able to highlight the relevance of stem cell molecular studies for future therapeutical approaches. The audience was particular interest in some new described approaches, such as isolation of circulating cancer stem cells, identified new biomarkers potentially transferable to other tumour types, and patients stratification importance.
Our next BioRN lounge will be on Tuesday May 15 as usual in the Kasselhaus by Urban Kitchen and will host Prof. Steffen Rupp, Director of the Department of Molecular Biotechnology and Deputy Director of Fraunhofer IGB.
BioRN is a life science research and industry cluster dedicated to the development of cell-specific, molecular and personalised innovative treatments. The BioRN Cluster stands for the development, networking, representation and promotion of the life science region into one of the leading life science clusters in Europe. The cluster-members include renowned academic research institutions such as the Universities of Heidelberg, the German Cancer Research Center (DKFZ) and the European Molecular Biology Laboratory (EMBL) and big pharmaceutical companies such as AbbVie, Boehringer Ingelheim, Johnson & Johnson, Merck, Roche, und Sanofi-Aventis, and about 80 small and medium-sized biotech enterprises. Beyond the members registered in the cluster, BioRN gives access to a wider network via partnerships and collaborations. In terms of the use of clusters for the internationalization of companies, BioRN has founded, together with Leuven (Belgium), Maastricht (Netherlands) and Copenhagen (Denmark), an alliance for the enforcement of biomedical innovation in Europe, called the Health Axis Europe.
HI-STEM gGmbH is a non-profit public-private partnership between the German Cancer Research Center (DKFZ) in Heidelberg and the Dietmar Hopp Stiftung. HI-STEM performs cutting-edge research on normal and malignant stem cells with the aim of translating these results into novel clinical applications. This includes the development of novel diagnostic tools and innovative therapies to monitor and target leukemic and solid tumor stem cells as well as metastatic disease. HI-STEM was founded in 2008 and is located on the fourth floor of the main building of the DKFZ. HI-STEM is made up of an international team of more than fifty scientists, including postdoctoral fellows, PhD and MSc. students as well as technical staff. This research team is spread over six topics and is directed by the managing director of HI-STEM, Professor Andreas Trumpp, as well as five additional group leaders.