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DKFZ: Defective DNA damage repair leads to chaos in the genome

On November 14, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation…

A faster lane towards effective therapies of childhood brain cancer

On November 6, 2018, Posted by , In News, By ,, , With Comments Off on A faster lane towards effective therapies of childhood brain cancer

Scientists of the „Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ), the German Cancer Consortium (DKTK) and the German Cancer Research Center (DKFZ), in collaboration with colleagues from Seattle, U.S.A., have built a collection of tumor models that can be used to test anticancer drugs for treating childhood brain…

DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

On November 6, 2018, Posted by , In News, By , , With Comments Off on DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

Scientists from the German Cancer Research Centre (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH) have identified a central switch protein in breast cancer that promotes tumor metastasis in response to cellular stress. The switch triggers a stem cell program in the cancer cells…

Sanofi joins Open Targets

On October 31, 2018, Posted by , In News, By , , With Comments Off on Sanofi joins Open Targets

Sanofi has joined Open Targets, the public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation. Public-private collaboration Open Targets announced today that Sanofi has joined its pioneering public-private collaboration to transform drug discovery by improving the success rate for developing new medicines. Sanofi’s expertise…

DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

On October 29, 2018, Posted by , In News, By , With Comments Off on DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

With its “Synergy Grants”, the ERC supports small teams of scientists working together to solve complex research problems, bringing together different techniques and skills across disciplines. “DECODE” Genes are team players. Changes in a genetic make-up often have an effect on the activity of a large number of other genes…

EMBL/Sanofi: More effective insulin thanks to first 3D image

On October 29, 2018, Posted by , In News, By , , With Comments Off on EMBL/Sanofi: More effective insulin thanks to first 3D image

An international collaboration has revealed how to make therapeutic insulins more effective than they currently are. The findings – published in Nature Communications on 24 October – will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide. Insulin receptor structural biology. IMAGE:…

PROGEN – 35 years passion for research

On October 29, 2018, Posted by , In News, With Comments Off on PROGEN – 35 years passion for research

35 years after PROGEN was founded by scientists of the German Cancer Research Center (DKFZ) and the University of Heidelberg in 1983, the company celebrated the anniversary of its antibody-based business on October 23rd with business partners, staff and two of the founders, Werner Franke and Ekkehard Bautz. In their…

European Health Catapult mentioned as one of the six best Biotech Startup Competition in Europe

On October 24, 2018, Posted by , In News, With Comments Off on European Health Catapult mentioned as one of the six best Biotech Startup Competition in Europe

The European Health Catapult has been mentioned as one of the 6 best Biotech Startup Competitions in Europe by labiotech. The programme is organized by EIT Health with the support of the Health Axis Europe (where BioRN is a member). Taking part in a pitch competition can help a biotech…

DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

On October 19, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

A certain form of lung cancer is characterized by two genes that are accidentally fused. The fusion produces a growth signal for the cells. These tumors respond well to a targeted drug that deprives the cancer cells of the growth stimulus. Several molecular variants of cancer-promoting gene fusion exist. Rocio…

Roche launches NGS AVENIO Tumor Tissue Analysis Kits for oncology research

On October 15, 2018, Posted by , In News, By , , With Comments Off on Roche launches NGS AVENIO Tumor Tissue Analysis Kits for oncology research

Ready-to-use kits determine genomic characteristics of solid tumours Optimized workflow to generate results in house Software analysis allows correlation to AVENIO ctDNA NGS kits Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the global commercial launch of three new next-generation sequencing (NGS) AVENIO Tumor Tissue Analysis Kits – the AVENIO…