News from the BioRN Cluster

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Europe’s top health start-ups in Biotech, Medtech and Digital Health win cash and recognition at EIT Health Summit

On December 17, 2018, Posted by , In News, By , With Comments Off on Europe’s top health start-ups in Biotech, Medtech and Digital Health win cash and recognition at EIT Health Summit

Finals held for European Health Catapult and Bootcamp pitch contest   SyNoesis, a start-up developing a cure for Parkinson’s Disease, Sleepiz, a contact-free device for home diagnosis of sleep apnea, and Aenitis, whose device improves sorting of cells in suspensions, were top winners in the three categories of the European…

Jan Korbel And Stefan Pfister Receive HMLS Investigator Award

On December 14, 2018, Posted by , In News, With Comments Off on Jan Korbel And Stefan Pfister Receive HMLS Investigator Award

Prize for Heidelberg Molecular Life Sciences endowed with 100,000 euros For their ongoing commitment to promote groundbreaking collaborations in Heidelberg and to establish new methods of research in the molecular life sciences, especially cancer research, Dr Jan Korbel and Prof. Dr Stefan Pfister will share this year’s HMLS Investigator Award….

VAXIMM Initiates Phase I/II Trial with VXM01 Oral T-cell Immunotherapy in Combination with PD-L1 Inhibitor Avelumab in Glioblastoma

On December 14, 2018, Posted by , In News, By , With Comments Off on VAXIMM Initiates Phase I/II Trial with VXM01 Oral T-cell Immunotherapy in Combination with PD-L1 Inhibitor Avelumab in Glioblastoma

VAXIMM AG, a Swiss/German biotech company focused on developing oral T-cell immunotherapies, today announced that the first patient has been dosed in a Phase I/II trial evaluating VXM01 oral immunotherapy in combination with avelumab*, a human anti-PD-L1 antibody, for the treatment of glioblastoma. The trial is part of a collaboration…

DKFZ/EMBL: Computer model to predict prostate cancer progress

On December 11, 2018, Posted by , In News, By , With Comments Off on DKFZ/EMBL: Computer model to predict prostate cancer progress

  IMAGE: Colourbox – Kiyoshi Takahase Segundo Cancer researchers have developed a computer model that can predict the course of disease for prostate cancer, based on cancer patient genomic and clinical data The model is currently being implemented at a prostate cancer clinic in Germany. The researchers have also found…

Baden-Württemberg awarded two research prizes to Heidelberg

On December 11, 2018, Posted by , In News, By , With Comments Off on Baden-Württemberg awarded two research prizes to Heidelberg

This year, the Landesforschungspreis Baden-Württemberg for excellence in applied research goes to Andreas Trumpp from the German Cancer Research Centre (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH). Theresia Bauer, Minister of Science, Research and the Arts, presented the 100,000 euro award at a…

Leibniz Prize for Hans-Reimer Rodewald (DKFZ)

On December 10, 2018, Posted by , In News, By , With Comments Off on Leibniz Prize for Hans-Reimer Rodewald (DKFZ)

Hans-Reimer Rodewald of the German Cancer Research Center receives the Gottfried Wilhelm Leibniz Prize 2019, the most important research award in Germany. Rodewald’s research revolves around the question of how the different types of immune cells develop from stem cells and together form a functional defence system. Hans-Reimer Rodewald ©…

Affimed Presents Data at ASH 2018 Substantiating Opportunity for AFM13 as Mono- and Combination Therapy in CD30-Positive Tumors

On December 10, 2018, Posted by , In News, By , With Comments Off on Affimed Presents Data at ASH 2018 Substantiating Opportunity for AFM13 as Mono- and Combination Therapy in CD30-Positive Tumors

Data Confirm Clinical Single-Agent Activity of AFM13 in CD30-Positive Lymphoma with Cutaneous Presentation and Doubled Complete Response Rate of AFM13 in Combination with Keytruda® (Pembrolizumab) in Hodgkin Lymphoma Patients Future Combination Opportunities Include Combination of CD16A Immune Cell Engagers with Adoptive NK Cell Transfer Heidelberg, Germany, December 3, 2018 –…

DKFZ/EMBL: New Ways to Look at Protein-RNA Networks

On December 10, 2018, Posted by , In News, By , , With Comments Off on DKFZ/EMBL: New Ways to Look at Protein-RNA Networks

For their vital tasks, all RNA molecules in our cells require proteins as binding partners. Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and colleagues from the European Molecular Biology Laboratory (EMBL) have developed the first method with which they can analyze the composition of the entire RNA-protein…

BioRN honorary membership for Prof. Stefan Meuer and Dr. Friedrich Richter

On December 6, 2018, Posted by , In Press Releases, With Comments Off on BioRN honorary membership for Prof. Stefan Meuer and Dr. Friedrich Richter

Heidelberg, 06.12.2018 BioRN 2018 Members’ assembly has been the occasion to award Prof. Stefan Meuer and Dr. Friedrich Richter with BioRN honorary membership for their long-lasting and outstanding contribution to the BioRN Network. Prof. S. Meuer and Dr. C. Tidona (Chair of BioRN Startegic Advisory Board) Dr. F. Richter and…

Solmic Research GmbH and the European Molecular Biology Laboratory enter into a research collaboration

On December 3, 2018, Posted by , In News, By , With Comments Off on Solmic Research GmbH and the European Molecular Biology Laboratory enter into a research collaboration

Solmic Research GmbH has entered into a research collaboration with the European Molecular Biology Laboratory (EMBL) with the goal to elucidate the mode of action of natural extracts. Natural extracts, such as active ingredients of plants, are the origin of medicine and are widely used for medical applications, especially in…

DKFZ/EMBL: Algorithm identifies multiple gene–environment relationships

On November 30, 2018, Posted by , In News, By , , With Comments Off on DKFZ/EMBL: Algorithm identifies multiple gene–environment relationships

Researchers at the German Cancer Research Center (DKFZ), EMBL’s European Bioinformatics Institute (EMBL-EBI) and the Wellcome Sanger Institute have developed a new computational method that makes it possible to identify the impact of hundreds of environmental factors on genotype–environment interactions. The method will enhance understanding of relationship between genotype and…

BioRN Lounge: Learning the physiological basis of the Cocktail Party effect with Eckhard Friauf from TU Kaiserslautern.

On November 28, 2018, Posted by , In Press Releases, By , With Comments Off on BioRN Lounge: Learning the physiological basis of the Cocktail Party effect with Eckhard Friauf from TU Kaiserslautern.

Heidelberg, 28.11.2018 Last BioRN Lounge of the year before the winter sleep, led us to the magical world of hearing.   As usual it was the occasion for life science companies as well for scientists from our research institutes, to meet and chat about latest news and achievements. The BioRN…

Cluster Management Excellence reconfirmed for the BioRN Network e.V..

On November 23, 2018, Posted by , In Press Releases, By , With Comments Off on Cluster Management Excellence reconfirmed for the BioRN Network e.V..

Heidelberg, 23.11.2018 BioRN Network e.V. has been recently awarded with the “Cluster Management Excellence Label SILVER – Proven for Cluster Excellence”. In 2008, the cluster successfully participated in the Leading-Edge Cluster Competition (“Spitzencluster-Wettbewerb”) of the German Federal Ministry of Education and Research (BMBF). In 2013, BioRN was awarded the “Cluster…

DKFZ: Defective DNA damage repair leads to chaos in the genome

On November 14, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation…

A faster lane towards effective therapies of childhood brain cancer

On November 6, 2018, Posted by , In News, By ,, , With Comments Off on A faster lane towards effective therapies of childhood brain cancer

Scientists of the „Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ), the German Cancer Consortium (DKTK) and the German Cancer Research Center (DKFZ), in collaboration with colleagues from Seattle, U.S.A., have built a collection of tumor models that can be used to test anticancer drugs for treating childhood brain…

DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

On November 6, 2018, Posted by , In News, By , , With Comments Off on DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

Scientists from the German Cancer Research Centre (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH) have identified a central switch protein in breast cancer that promotes tumor metastasis in response to cellular stress. The switch triggers a stem cell program in the cancer cells…

Sanofi joins Open Targets

On October 31, 2018, Posted by , In News, By , , With Comments Off on Sanofi joins Open Targets

Sanofi has joined Open Targets, the public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation. Public-private collaboration Open Targets announced today that Sanofi has joined its pioneering public-private collaboration to transform drug discovery by improving the success rate for developing new medicines. Sanofi’s expertise…

DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

On October 29, 2018, Posted by , In News, By , With Comments Off on DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

With its “Synergy Grants”, the ERC supports small teams of scientists working together to solve complex research problems, bringing together different techniques and skills across disciplines. “DECODE” Genes are team players. Changes in a genetic make-up often have an effect on the activity of a large number of other genes…

EMBL/Sanofi: More effective insulin thanks to first 3D image

On October 29, 2018, Posted by , In News, By , , With Comments Off on EMBL/Sanofi: More effective insulin thanks to first 3D image

An international collaboration has revealed how to make therapeutic insulins more effective than they currently are. The findings – published in Nature Communications on 24 October – will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide. Insulin receptor structural biology. IMAGE:…

PROGEN – 35 years passion for research

On October 29, 2018, Posted by , In News, With Comments Off on PROGEN – 35 years passion for research

35 years after PROGEN was founded by scientists of the German Cancer Research Center (DKFZ) and the University of Heidelberg in 1983, the company celebrated the anniversary of its antibody-based business on October 23rd with business partners, staff and two of the founders, Werner Franke and Ekkehard Bautz. In their…