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DKFZ: Sugar metabolism controls intestinal regeneration

On September 19, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Sugar metabolism controls intestinal regeneration

Scientists from the German Cancer Research Center and Heidelberg University have discovered a surprising connection between sugar metabolism and the adaptation of intestinal tissue to the nutritional state. Section from the intestine of a fruit fly: Stem cells are labelled green (GFP). © M. Boutros/DKFZ No other tissue in our…

DKFZ: A healthy lifestyle reduces the risk of colon cancer – regardless of the genetic risk profile

On September 18, 2018, Posted by , In News, By , , With Comments Off on DKFZ: A healthy lifestyle reduces the risk of colon cancer – regardless of the genetic risk profile

The risk of developing bowel cancer depends, among other things, on lifestyle. Scientists from the German Cancer Research Center were able to show that everyone can reduce their personal risk of colon cancer by combining as many of five healthy lifestyles as possible: non-smoking, low alcohol consumption, a healthy diet,…

EUROoC network lays the foundation for joint European organ-on-a-chip research

On September 17, 2018, Posted by , In News, By , , With Comments Off on EUROoC network lays the foundation for joint European organ-on-a-chip research

The Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB is coordinating the establishment of a European research network to promote organ-on-a-chip technology. This enables the replication of human organs on a micro scale and is considered a technology with great potential, among other things for the research of new pharmaceutical…

Partnering for Innovation at the Heidelberg Science Day

On September 12, 2018, Posted by , In Press Releases, By , With Comments Off on Partnering for Innovation at the Heidelberg Science Day

Heidelberg, 12.09.2018 To foster innovation and to keep providing cutting-edge science and technology, global healthcare companies are more and more closely collaborating with partners all over the world. The BMBF funded ‘Health Axis Europe Partnering’ (HAEP -) project in which BioRN has the project lead works as interface between innovation…

DKFZ: Figures for Germany determined for the first time: Avoidable risk factors cause 37 percent of all cancer cases

On September 10, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Figures for Germany determined for the first time: Avoidable risk factors cause 37 percent of all cancer cases

How many cancer cases in Germany are attributable to risk factors that we can influence ourselves? How many cancer cases are linked to cigarette smoking, being overweight or physical inactivity and, thus, are potentially preventable? Scientists from the German Cancer Research Center (DKFZ) have now calculated these figures for Germany…

Heidelberg University: Precise and Highly Efficient Gene Repair

On August 30, 2018, Posted by , In News, By , , With Comments Off on Heidelberg University: Precise and Highly Efficient Gene Repair

Heidelberg researchers develop new CRISPR/Cas process using Japanese ricefish   Photo: Gutierrez-Triana, Tavhelidse, Thumberger et al., 2018, figure three, subject to CC BY 4.0 license. Medaka embryo, in which the Rx2 gene – a gene critical for eye development – was edited with a repair copy. This copy contains the…

Affimed Announces Collaboration with Genentech to Develop Novel NK Cell Engager – based Immunotherapeutics for Multiple Cancer Targets

On August 29, 2018, Posted by , In News, By , , With Comments Off on Affimed Announces Collaboration with Genentech to Develop Novel NK Cell Engager – based Immunotherapeutics for Multiple Cancer Targets

Affimed will receive $96 million upfront and committed funding and is eligible for up to an additional $5.0 billion including milestone payments, and royalties on sales. Affimed will apply its proprietary Redirected Optimized Cell Killing (ROCK®) platform, which enables the generation of both NK cell and T cell-engaging antibodies, to…

Heidelberg University: Protection For Nerve Cells Delivered Through The Nose

On August 27, 2018, Posted by , In News, By , , With Comments Off on Heidelberg University: Protection For Nerve Cells Delivered Through The Nose

Material and picture: Dr Bettina Buchthal. Brain sections of control-treated (bottom) and nasal Activin A-treated (top) mice after a stroke. The white line marks the border between the healthy and damaged brain regions. Protective proteins that mitigate the destruction of nerve cells after a stroke can be administered into the…

HS-Analysis: how softwares can contribute to cancer treatment development

On August 23, 2018, Posted by , In News, By , , With Comments Off on HS-Analysis: how softwares can contribute to cancer treatment development

Finding a cure to any type of cancer is one of the biggest challenge in medicine. HS-Analysis wants to bring the concer research forward with the help of a software. Read about the plans of Sergey Biniaminov (Managing Director of HS Analysis) in the interview with ka-news (in German).

EMBL: New approach for testing cancer drug response

On August 23, 2018, Posted by , In News, By , , With Comments Off on EMBL: New approach for testing cancer drug response

  New approach uses inherited genome to test cancer drug response. PHOTO: iStock Large-scale systematic analysis explores how inherited genome effects drug response of cancer cells Patients with seemingly similar cancer tumours can respond differently to the same treatment. Over the last decades, scientists have been studying the molecular signatures…

Triple ERC success for DKFZ junior researchers

On August 15, 2018, Posted by , In News, By , , With Comments Off on Triple ERC success for DKFZ junior researchers

The European Research Council (ERC) awards Starting Grants to support excellent young scientists when they are starting an independent science career. In this year’s round of proposals, three scientists from the German Cancer Research Center (DKFZ) have been chosen at once for the prestigious award: Ana Banito, Fabian Erdel and…

FAZ: Heidelberg attracts researchers and physician

On August 15, 2018, Posted by , In News, With Comments Off on FAZ: Heidelberg attracts researchers and physician

The Frankfurter Allgemeine Zeitung recently published an article about the biotech/life science cluster that developed around the region of Heidelberg in the past decades. André Domin (Managing Director of the Technology Park Heidelberg and member of the BioRN Network e.V. executive board) reported on the funding for the new technology…

DKFZ: Combined imaging provides more information about the tumor

On August 13, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Combined imaging provides more information about the tumor

The German Cancer Research Center (DKFZ) has installed the world’s first combined device combining a 9.4 Tesla high-field MRI with a PET scanner. In combination, the two imaging methods provide significantly more information about tumors. © S. Kegel/DKFZ A variety of imaging procedures provide insights into the body’s interior. Each…

Fraunhofer IGB: Third place for Retina-on-a-chip project at the Science2Start competition

On July 30, 2018, Posted by , In News, By , , With Comments Off on Fraunhofer IGB: Third place for Retina-on-a-chip project at the Science2Start competition

At the annual Science2Start competition organized by BioRegio STERN Management GmbH, Dr. Ing. Christopher Probst, scientist in the Organ-on-a-Chip group of the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB, reached place 3 with the Retina-on-a-Chip project. With “Retina-on-a-Chip”, scientists at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB…

Heidelberg University Hospital/ HITS/ ZMBH: The need for speed – Why malaria parasites are faster than human immune cells

On July 23, 2018, Posted by , In News, By , With Comments Off on Heidelberg University Hospital/ HITS/ ZMBH: The need for speed – Why malaria parasites are faster than human immune cells

Elementary cytoskeleton protein is different in parasites and represents a starting point for a possible new therapy against malaria infections. Researchers from the Heidelberg University Hospital, the Centre for Molecular Biology at the University of Heidelberg (ZMBH), and the Heidelberg Institute for Theoretical Studies (HITS) have published these findings in…

PEPperPRINT granted new US patent

On July 18, 2018, Posted by , In News, By , With Comments Off on PEPperPRINT granted new US patent

PEPperPRINT latest patent covers a novel method for producing high-density peptide microarrays PEPperPRINT is pleased to announce that the United States Patent and Trademark Office (USPTO) has issued U.S. Patent No. 9,925,509 covering a method for the generation of high-density peptide microarrays by means of a combinatorial laser induced forward…

EMBL scientists show that mammalian life begins differently than we thought

On July 16, 2018, Posted by , In News, By , , With Comments Off on EMBL scientists show that mammalian life begins differently than we thought

It was long thought that during an embryo’s first cell division, one spindle is responsible for segregating the embryo’s chromosomes into two cells. EMBL scientists now show that in mice, there are actually two spindles, one for each set of parental chromosomes, meaning that the genetic information from each parent…

HITS: New computational method for drug discovery

On July 12, 2018, Posted by , In News, By , , With Comments Off on HITS: New computational method for drug discovery

HITS researchers developed tauRAMD, a tool to predict drug-target residence times from short simulations. The method is illustrated on the cover page of July 2018 issue of the Journal of Chemical Theory and Computation, software is freely available. The graphical image used for the cover of the JCTC . Image:…

DKFZ: Mechanism of action of a diabetes drug differs between males and females

On July 11, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Mechanism of action of a diabetes drug differs between males and females

Most diabetes medications do not attack the cause of the disease. Glitazones are different: they improve insulin sensitivity and can promote the conversion of unhealthy white adipose tissue into fat-burning beige adipocytes. However, due to their side effects, they are hardly used. Scientists from the German Cancer Research Center are…

DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

On July 11, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune system, scientists from the German Cancer Research Center (DKFZ), the University Hospitals in Mannheim and Heidelberg, and the German Cancer Consortium now report. It thus blocks…