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DKFZ: Defective DNA damage repair leads to chaos in the genome

On November 14, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Defective DNA damage repair leads to chaos in the genome

Scientists at the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) have now found a cause for the frequent catastrophic events in the genetic material of cancer cells that have only been known for a few years: If an important DNA repair system of the cells has failed, this promotes fragmentation…

A faster lane towards effective therapies of childhood brain cancer

On November 6, 2018, Posted by , In News, By ,, , With Comments Off on A faster lane towards effective therapies of childhood brain cancer

Scientists of the „Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ), the German Cancer Consortium (DKTK) and the German Cancer Research Center (DKFZ), in collaboration with colleagues from Seattle, U.S.A., have built a collection of tumor models that can be used to test anticancer drugs for treating childhood brain…

DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

On November 6, 2018, Posted by , In News, By , , With Comments Off on DKFZ/HI-STEM – Breast cancer: Stress signaling promotes metastasis and therapy resistance

Scientists from the German Cancer Research Centre (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM gGmbH) have identified a central switch protein in breast cancer that promotes tumor metastasis in response to cellular stress. The switch triggers a stem cell program in the cancer cells…

Sanofi joins Open Targets

On October 31, 2018, Posted by , In News, By , , With Comments Off on Sanofi joins Open Targets

Sanofi has joined Open Targets, the public-private partnership that uses human genetics and genomics data for systematic drug target identification and prioritisation. Public-private collaboration Open Targets announced today that Sanofi has joined its pioneering public-private collaboration to transform drug discovery by improving the success rate for developing new medicines. Sanofi’s expertise…

DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

On October 29, 2018, Posted by , In News, By , With Comments Off on DKFZ/EMBL/Heidelberg University: two ERC Synergy Grants for Heidelberg

With its “Synergy Grants”, the ERC supports small teams of scientists working together to solve complex research problems, bringing together different techniques and skills across disciplines. “DECODE” Genes are team players. Changes in a genetic make-up often have an effect on the activity of a large number of other genes…

EMBL/Sanofi: More effective insulin thanks to first 3D image

On October 29, 2018, Posted by , In News, By , , With Comments Off on EMBL/Sanofi: More effective insulin thanks to first 3D image

An international collaboration has revealed how to make therapeutic insulins more effective than they currently are. The findings – published in Nature Communications on 24 October – will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide. Insulin receptor structural biology. IMAGE:…

PROGEN – 35 years passion for research

On October 29, 2018, Posted by , In News, With Comments Off on PROGEN – 35 years passion for research

35 years after PROGEN was founded by scientists of the German Cancer Research Center (DKFZ) and the University of Heidelberg in 1983, the company celebrated the anniversary of its antibody-based business on October 23rd with business partners, staff and two of the founders, Werner Franke and Ekkehard Bautz. In their…

Immune oncology and beyond at the first joint BioRN and Ci3 Annual Conference

On October 26, 2018, Posted by , In Press Releases, By , , With Comments Off on Immune oncology and beyond at the first joint BioRN and Ci3 Annual Conference

Darmstadt, October 26, 2018 The BioRN Life Science Cluster Rhine-Neckar in Heidelberg and the Cluster for Individualized ImmuneIntervention (Ci3) in Mainz were the organizers of yesterday’s Joint BioRN & Ci3 Annual Conference titled “Immunotherapy and beyond – The next generation of cancer treatment“. 200 participants – members and partners of…

European Health Catapult mentioned as one of the six best Biotech Startup Competition in Europe

On October 24, 2018, Posted by , In News, With Comments Off on European Health Catapult mentioned as one of the six best Biotech Startup Competition in Europe

The European Health Catapult has been mentioned as one of the 6 best Biotech Startup Competitions in Europe by labiotech. The programme is organized by EIT Health with the support of the Health Axis Europe (where BioRN is a member). Taking part in a pitch competition can help a biotech…

Julia Schaft appointed new Managing Director at BioRN

On October 22, 2018, Posted by , In Press Releases, With Comments Off on Julia Schaft appointed new Managing Director at BioRN

Heidelberg, 22.10.2018 Effective September 30, 2018, Fritz Richter retired from his roles as Managing Director of the BioRN Network e.V. and the BioRN Cluster Management GmbH, although he will stay actively connected to the organization. We are pleased to announce that the boards of BioRN Network e.V. and BioRN Cluster…

DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

On October 19, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

A certain form of lung cancer is characterized by two genes that are accidentally fused. The fusion produces a growth signal for the cells. These tumors respond well to a targeted drug that deprives the cancer cells of the growth stimulus. Several molecular variants of cancer-promoting gene fusion exist. Rocio…

Roche launches NGS AVENIO Tumor Tissue Analysis Kits for oncology research

On October 15, 2018, Posted by , In News, By , , With Comments Off on Roche launches NGS AVENIO Tumor Tissue Analysis Kits for oncology research

Ready-to-use kits determine genomic characteristics of solid tumours Optimized workflow to generate results in house Software analysis allows correlation to AVENIO ctDNA NGS kits Roche (SIX: RO, ROG; OTCQX: RHHBY) today announced the global commercial launch of three new next-generation sequencing (NGS) AVENIO Tumor Tissue Analysis Kits – the AVENIO…

BioRN Lounge: Heike A. Wieland reported on a freshly established research collaboration in Heidelberg.

On October 10, 2018, Posted by , In Press Releases, By , With Comments Off on BioRN Lounge: Heike A. Wieland reported on a freshly established research collaboration in Heidelberg.

Heidelberg, 10.10.2018 After the long summer break, the BioRN Lounge was the occasion for life science companies as well for scientists from our research institutes, to meet and chat about latest news and achievements. The BioRN Lounge is the prime monthly networking event for BioRN members. It is the occasion…

DKFZ: Machine Learning to Accellerate Drug Research

On October 10, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Machine Learning to Accellerate Drug Research

The European Research Council (ERC) is awarding a “proof-of-concept grant” to scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Heidelberg University for the first time to enable them to develop new drugs more cheaply and quickly using image-based analyses. Automated microscopy documents changes in cells after…

Jörg Debatin to chair the supervisory board of Hummingbird Diagnostics GmbH

On October 9, 2018, Posted by , In News, With Comments Off on Jörg Debatin to chair the supervisory board of Hummingbird Diagnostics GmbH

International healthcare leader strengthens miRNA experts Hummingbird Diagnostics GmbH announced that Prof. Dr. med. Jörg Debatin is appointed Chairman of the Supervisory Board with immediate effect. The former Vice President and Chief Technology Officer of GE Healthcare and CEO of Amedes AG directed the University Hospital Hamburg-Eppendorf for 8 years…

Heidelberg University: Highly Organised Process: How Protein Complexes Form in the Cell

On October 8, 2018, Posted by , In News, By , With Comments Off on Heidelberg University: Highly Organised Process: How Protein Complexes Form in the Cell

Heidelberg researchers gain fundamental new insights into synthesis of biologically active complexes. The formation of protein complexes is a highly organised process that does not begin with the “finished” proteins. Studies conducted by researchers at the Center for Molecular Biology of Heidelberg University (ZMBH) and the German Cancer Research Center…

Breast cancer: Towards individualized therapy

On October 8, 2018, Posted by , In News, By , , With Comments Off on Breast cancer: Towards individualized therapy

Breast cancer is as manifold as are those who are affected. Therefore, scientists and physicians from the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD) and the National Center for Tumor Diseases (NCT) in Heidelberg are generating genetic profiles from metastatic tissue samples before they choose, on this basis,…

Preclinical Efficacy Data of Apogenix’ HERA – CD27L Published in Frontiers in Oncology

On October 4, 2018, Posted by , In News, By , With Comments Off on Preclinical Efficacy Data of Apogenix’ HERA – CD27L Published in Frontiers in Oncology

Apogenix, a biopharmaceutical company developing next generation immuno-oncology therapeutics, announced today that new data published in the current volume of Frontiers in Oncology demonstrate the potent anti – tumor efficacy of Apogenix’ HERA – CD27L. In contrast to antibodies in development, HERA – CD27L is the first true CD27 receptor…

Is it possible to pitch the full potential of discoveries without spilling the secret sauce?

On October 4, 2018, Posted by , In Press Releases, By , , With Comments Off on Is it possible to pitch the full potential of discoveries without spilling the secret sauce?

Heidelberg, 04.10.2018 On Tuesday October 2, Guenter Huhle, Head of JLABS EMEA, Johnson & Johnson Innovation shared key insights on the art of pitching in front of a packed audience of researchers, entrepreneurs and professionals mainly from the Heidelberg area.   Panel discussion: Maciek Drozdz (Principal of Venture Investments for…

EMBL & Heidelberg University: Ageing is visible in the way cells use glucose

On October 2, 2018, Posted by , In News, With Comments Off on EMBL & Heidelberg University: Ageing is visible in the way cells use glucose

EMBL researchers and collaborators unveil the molecular mechanisms of ageing in human stem cells Getting older means a few more wrinkles and grey hairs. Deep down, ageing also entails a functional decline of your cells and especially of stem cells. A research team from EMBL and Heidelberg University has studied…