DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

On October 19, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Takeda Oncology Research Award 2018 to Rocio Sotillo

A certain form of lung cancer is characterized by two genes that are accidentally fused. The fusion produces a growth signal for the cells. These tumors respond well to a targeted drug that deprives the cancer cells of the growth stimulus. Several molecular variants of cancer-promoting gene fusion exist. Rocio…

DKFZ: Machine Learning to Accellerate Drug Research

On October 10, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Machine Learning to Accellerate Drug Research

The European Research Council (ERC) is awarding a “proof-of-concept grant” to scientists from the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) and the Heidelberg University for the first time to enable them to develop new drugs more cheaply and quickly using image-based analyses. Automated microscopy documents changes in cells after…

Breast cancer: Towards individualized therapy

On October 8, 2018, Posted by , In News, By , , With Comments Off on Breast cancer: Towards individualized therapy

Breast cancer is as manifold as are those who are affected. Therefore, scientists and physicians from the German Cancer Research Center (DKFZ), Heidelberg University Hospital (UKHD) and the National Center for Tumor Diseases (NCT) in Heidelberg are generating genetic profiles from metastatic tissue samples before they choose, on this basis,…

DKFZ: Sugar metabolism controls intestinal regeneration

On September 19, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Sugar metabolism controls intestinal regeneration

Scientists from the German Cancer Research Center and Heidelberg University have discovered a surprising connection between sugar metabolism and the adaptation of intestinal tissue to the nutritional state. Section from the intestine of a fruit fly: Stem cells are labelled green (GFP). © M. Boutros/DKFZ No other tissue in our…

DKFZ: A healthy lifestyle reduces the risk of colon cancer – regardless of the genetic risk profile

On September 18, 2018, Posted by , In News, By , , With Comments Off on DKFZ: A healthy lifestyle reduces the risk of colon cancer – regardless of the genetic risk profile

The risk of developing bowel cancer depends, among other things, on lifestyle. Scientists from the German Cancer Research Center were able to show that everyone can reduce their personal risk of colon cancer by combining as many of five healthy lifestyles as possible: non-smoking, low alcohol consumption, a healthy diet,…

DKFZ: Figures for Germany determined for the first time: Avoidable risk factors cause 37 percent of all cancer cases

On September 10, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Figures for Germany determined for the first time: Avoidable risk factors cause 37 percent of all cancer cases

How many cancer cases in Germany are attributable to risk factors that we can influence ourselves? How many cancer cases are linked to cigarette smoking, being overweight or physical inactivity and, thus, are potentially preventable? Scientists from the German Cancer Research Center (DKFZ) have now calculated these figures for Germany…

Triple ERC success for DKFZ junior researchers

On August 15, 2018, Posted by , In News, By , , With Comments Off on Triple ERC success for DKFZ junior researchers

The European Research Council (ERC) awards Starting Grants to support excellent young scientists when they are starting an independent science career. In this year’s round of proposals, three scientists from the German Cancer Research Center (DKFZ) have been chosen at once for the prestigious award: Ana Banito, Fabian Erdel and…

DKFZ: Combined imaging provides more information about the tumor

On August 13, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Combined imaging provides more information about the tumor

The German Cancer Research Center (DKFZ) has installed the world’s first combined device combining a 9.4 Tesla high-field MRI with a PET scanner. In combination, the two imaging methods provide significantly more information about tumors. © S. Kegel/DKFZ A variety of imaging procedures provide insights into the body’s interior. Each…

DKFZ: Mechanism of action of a diabetes drug differs between males and females

On July 11, 2018, Posted by , In News, By , , With Comments Off on DKFZ: Mechanism of action of a diabetes drug differs between males and females

Most diabetes medications do not attack the cause of the disease. Glitazones are different: they improve insulin sensitivity and can promote the conversion of unhealthy white adipose tissue into fat-burning beige adipocytes. However, due to their side effects, they are hardly used. Scientists from the German Cancer Research Center are…

DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

On July 11, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune system, scientists from the German Cancer Research Center (DKFZ), the University Hospitals in Mannheim and Heidelberg, and the German Cancer Consortium now report. It thus blocks…