EMBL scientists show that mammalian life begins differently than we thought

On July 16, 2018, Posted by , In News, By , , With Comments Off on EMBL scientists show that mammalian life begins differently than we thought

It was long thought that during an embryo’s first cell division, one spindle is responsible for segregating the embryo’s chromosomes into two cells. EMBL scientists now show that in mice, there are actually two spindles, one for each set of parental chromosomes, meaning that the genetic information from each parent…

EMBL: Combining antibiotics changes their effectiveness

On July 5, 2018, Posted by , In News, By , With Comments Off on EMBL: Combining antibiotics changes their effectiveness

The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives, EMBL researchers show. Depending on the bacterial species, some combinations stop antibiotics from working to their full potential whilst others begin to defeat antibiotic resistance, report EMBL researchers and collaborators…

EMBL: Miniature testing of drug pairs on tumour biopsies

On June 25, 2018, Posted by , In News, By ,, , With Comments Off on EMBL: Miniature testing of drug pairs on tumour biopsies

Microfluidic device in the Merten lab. IMAGE – Ramesh Utharala, EMBL Combinations of cancer drugs can be quickly and cheaply tested on tumour cells using a novel device developed by EMBL scientists. The research, reported in Nature Communications on June 22, marks the latest advancement in the field of personalised…

EMBL: Constructing new tissue shapes with light

On June 19, 2018, Posted by , In News, By , , With Comments Off on EMBL: Constructing new tissue shapes with light

Two examples of the tissue shapes the team created. IMAGE: Stefano De Renzis/EMBL EMBL researchers guide the shape of cells and tissues with optogenetics Constructing biological tissues, such as skin, muscle, or bone, in customized shapes is now one step closer. Researchers at EMBL have succeeded in guiding the folding…

Roche joins EMBL’s Corporate Partnership Programme

On June 12, 2018, Posted by , In News, By ,, , With Comments Off on Roche joins EMBL’s Corporate Partnership Programme

Roche and EMBL join forces to create new training opportunities for young researchers                               EMBL welcomes Roche, a frontrunner in personalised healthcare and leading provider of in vitro diagnostics, to the EMBL Advanced Training Centre Corporate Partnership Programme. The new partners will develop advanced training for young investigators and the…

DKFZ/HD Uni Hospital/EMBL: Genetic analysis for certain childhood brain tumors soon a standard-of-care?

On May 14, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ/HD Uni Hospital/EMBL: Genetic analysis for certain childhood brain tumors soon a standard-of-care?

An international team of researchers from the Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), the European Molecular Biology Laboratory (EMBL) and the German Cancer Consortium (DKTK) together with colleagues at the St. Jude Children’s Research Hospital in Memphis and the Hospital for Sick Children in Toronto has summarized…

EMBL – CRISPR: from clipping scissors to word processor

On May 8, 2018, Posted by , In News, By ,, , With Comments Off on EMBL – CRISPR: from clipping scissors to word processor

Barcodes are used in a new way in the MAGESTIC platform, adding a new level of precision to CRISPR gene editing. Credit: Kelly Irvine/NIST Using the gene-editing tool CRISPR to snip at DNA is often akin to using scissors to edit a newspaper article. You can cut out words, but it’s…

EMBL: Protein stability and solubility during cell cycle

On May 3, 2018, Posted by , In News, By , , With Comments Off on EMBL: Protein stability and solubility during cell cycle

  Dividing cell colored in a heat gradient, highlighting the variation in proteins’ thermal stability within and between different cell cycle stages. IMAGE: Aleksandra Krolik / EMBL EMBL scientists uncover large solubility and thermal stability changes of proteins during cell cycle The cell cycle is a highly dynamic process that…

EMBL: PDX Finder – Free global portal for cancer models

On April 9, 2018, Posted by , In News, By , With Comments Off on EMBL: PDX Finder – Free global portal for cancer models

First global online catalogue of PDX models facilitates collaboration and helps cancer researchers save valuable time The European Bioinformatics Institute (EMBL-EBI) and The Jackson Laboratory (JAX) have jointly developed the first open cancer research portal for Patient Derived Xenograft (PDX) models. The freely available PDX Finder is hosted by EMBL-EBI…

DKFZ: Blood test indicates risk of developing Alzheimer’s disease

On April 9, 2018, Posted by , In Research Article, By ,, , With Comments Off on DKFZ: Blood test indicates risk of developing Alzheimer’s disease

A newly developed blood test may indicate Alzheimer’s disease on average eight years before the clinical diagnosis. This was demonstrated by scientists from the Ruhr University Bochum (RUB), the German Cancer Research Center (DKFZ) and the Saarland Cancer Registry with a large population-based cohort study from the Saarland. Pathological deposits…