DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

On July 11, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Brain cancer – Typical mutation in cancer cells stifles immune response

The exchange of a single amino acid building block in a metabolic enzyme can lead to cancer. In addition, it can impair the immune system, scientists from the German Cancer Research Center (DKFZ), the University Hospitals in Mannheim and Heidelberg, and the German Cancer Consortium now report. It thus blocks…

BioRN Lounge: Dr. Juergen Gamer talked about Apogenix attractive immuno-oncology pipeline.

On June 27, 2018, Posted by , In Press Releases, By , , With Comments Off on BioRN Lounge: Dr. Juergen Gamer talked about Apogenix attractive immuno-oncology pipeline.

Heidelberg, 27.06.2018 BioRN Lounge: Dr. Juergen Gamer talked about “TNF Superfamily Receptor Modulators – Innovative Immuno-oncology Therapeutics” Once again, the BioRN Lounge was the occasion for the life science companies as well for scientists from our research institutes, to meet and chat about latest news and achievements. The BioRN Lounge…

DKFZ/Heidelberg University: New therapy makes blood cancer cells visible for the immune system

On June 27, 2018, Posted by , In News, By , , With Comments Off on DKFZ/Heidelberg University: New therapy makes blood cancer cells visible for the immune system

Chronic lymphocytic leukemia (CLL) is the most common type of blood cancer in adults. It can be treated with chemotherapy and oral drugs but this treatment cannot cure the cancer completely. Although the human immune system is capable of fighting the cancer cells, it often fails to notice them early…

DKFZ: 14 new breast cancer risk genes discovered

On June 26, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: 14 new breast cancer risk genes discovered

Many genetic markers associated with the familial breast cancer risk are outside the protein-coding regions of the genome and are likely to regulate the activity of neighboring genes. In a large international network, in which numerous DKFZ researchers were also involved, scientists have now combined genome-wide association studies with an…

EMBL: Miniature testing of drug pairs on tumour biopsies

On June 25, 2018, Posted by , In News, By ,, , With Comments Off on EMBL: Miniature testing of drug pairs on tumour biopsies

Microfluidic device in the Merten lab. IMAGE – Ramesh Utharala, EMBL Combinations of cancer drugs can be quickly and cheaply tested on tumour cells using a novel device developed by EMBL scientists. The research, reported in Nature Communications on June 22, marks the latest advancement in the field of personalised…

DKFZ: Breast cancer – Microproteins essential for cancer growth

On June 1, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: Breast cancer – Microproteins essential for cancer growth

Breast cancer is one of the leading causes of death in women worldwide. In order to develop new therapies, it is necessary to understand exactly how breast cancer cells function. Scientists at the German Cancer Research Center have taken an important step in this direction: In tumor tissue from breast…

DKFZ/HD Uni Hospital/EMBL: Genetic analysis for certain childhood brain tumors soon a standard-of-care?

On May 14, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ/HD Uni Hospital/EMBL: Genetic analysis for certain childhood brain tumors soon a standard-of-care?

An international team of researchers from the Hopp Children’s Cancer Center at the NCT Heidelberg (KiTZ), the European Molecular Biology Laboratory (EMBL) and the German Cancer Consortium (DKTK) together with colleagues at the St. Jude Children’s Research Hospital in Memphis and the Hospital for Sick Children in Toronto has summarized…

DKFZ: High science distinction for Michael Baumann

On May 9, 2018, Posted by , In News, By ,, , With Comments Off on DKFZ: High science distinction for Michael Baumann

At its 100th Annual Meeting, the American Radium Society honored Michael Baumann, Chairman and Scientific Director of the German Cancer Research Center (DKFZ), with the Janeway Gold Medal. The medal, which is awarded for outstanding contributions in cancer therapy, is one of the most prestigious distinctions in radiation oncology. Michael…

BioMed X and Merck extend research collaboration in oncology

On May 8, 2018, Posted by , In News, By ,, , With Comments Off on BioMed X and Merck extend research collaboration in oncology

BioMed X announced the start of a new research project in collaboration with Merck at its Innovation Center in Heidelberg. The new team will focus on the identification of novel approaches to exploit tumor-specific RNA splicing alterations for targeted cancer therapy.     Dr. Jan Mauer, who joined the BioMed X…