Cleavage Product of Alzheimer’s Key Protein APP Stimulates Nerve Cell Communication

On April 17, 2018, Posted by , In Research Article, By ,, , With Comments Off on Cleavage Product of Alzheimer’s Key Protein APP Stimulates Nerve Cell Communication

Neuroprotective role of APPsα: A histological section through the hippocampus is depicted in the background. The red staining shows APPsα in neuronal cell bodies. The green staining shows the dendritic processes of nerve cells. Source: Max Richter, Müller research group A cleavage product of the Alzheimer’s APP protein stimulates nerve…

DKFZ: Blood test indicates risk of developing Alzheimer’s disease

On April 9, 2018, Posted by , In Research Article, By ,, , With Comments Off on DKFZ: Blood test indicates risk of developing Alzheimer’s disease

A newly developed blood test may indicate Alzheimer’s disease on average eight years before the clinical diagnosis. This was demonstrated by scientists from the Ruhr University Bochum (RUB), the German Cancer Research Center (DKFZ) and the Saarland Cancer Registry with a large population-based cohort study from the Saarland. Pathological deposits…

EMBL: microglia nibbling on brain synapses (captured on film)

On March 27, 2018, Posted by , In Research Article, By ,, , With Comments Off on EMBL: microglia nibbling on brain synapses (captured on film)

For the first time, EMBL researchers have captured microglia nibbling on brain synapses. Their findings show that the special glial cells help synapses grow and rearrange, demonstrating the essential role of microglia in brain development. Nature Communications publishes the results on March 26. Multiple synapse heads send out filopodia (green)…

EMBL: Potential new way to limit antibiotic resistance spreading

On March 19, 2018, Posted by , In Research Article, By , , With Comments Off on EMBL: Potential new way to limit antibiotic resistance spreading

Potential new way to limit antibiotic resistance spreading. IMAGE: Aleksandra Krolik / EMBL EMBL scientists unravel the molecular basis of a major antibiotic resistance transfer mechanism One of the biggest current threats to global health is the rise of multi-drug resistant bacteria, caused by the spreading of antibiotic resistance amongst…

EMBL: Chromatin usage reveals developmental trajectories

On March 15, 2018, Posted by , In Research Article, By , , With Comments Off on EMBL: Chromatin usage reveals developmental trajectories

Information (arrows) emanating out of chromatin to give rise to different cell types. IMAGE: Campbell Medical Illustration EMBL scientists show how chromatin usage in individual cells reveals developmental trajectories Both cell type and developmental stage can be deduced from measurements of chromatin accessibility in thousands of single cells, researchers at…

NCT Heidelberg: Combination therapy in neuroblastoma: It`s all about the mix

On March 13, 2018, Posted by , In Research Article, By , , With Comments Off on NCT Heidelberg: Combination therapy in neuroblastoma: It`s all about the mix

The combination of two cell division inhibitors causes malignant nervous system tumors to die off, as scientists from the “Hopp Children’s Cancer Center at the NCT Heidelberg” (KiTZ) have shown in experimental studies.The combination strategy could be the key to new targeted therapies against this aggressive type of tumor. The…