Webinar: Advancing medicinal chemistry with high-throughput low-volume liquid handling

Developing pharmaceutical compounds with improved efficacy and specificity profiles means manipulating small molecules at the nanoscale. Since a molecule’s structure determines its function, approaches that access diverse molecular structures are crucial.

Advances in computational methods and automation have significantly enhanced medicinal chemists’ ability to explore vast chemical spaces and validate novel compounds at scale. For example, by integrating virtual screening with high-throughput experimentation (HTE), scientists can iteratively prioritize, validate, and optimize promising candidates, shortening discovery and development timelines.

In this webinar, we will explore how automation—particularly low-volume liquid handling—drives throughput in medicinal chemistry by increasing the number of data points generated per nanomolar-scale experiment. We will also discuss how positive displacement technology overcomes challenges in reproducibility by enabling precise handling of difficult-to-manage liquids at ultra-low volumes. Case studies from leading research institutes will highlight how these technologies are successfully advancing scientific progress.