Research

Tumor cells circulating in the blood are the “germ cells” of breast cancer metastases. They are very rare and could not be propagated in the culture dish until now, which made research into therapy resistance difficult. A team from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM* and the NCT Heidelberg** […]

Heidelberg, Germany, 19.12.2024 – RHEACELL today received approval from the European Medicines Agency (EMA) for its blinded, multi-centric Phase-3 trial (NCT06489028) evaluating allo-APZ2-CVU in patients with chronic venous ulcers (CVU). The pivotal trial will be conducted at more than 100 sites and is expected to enroll 250 patients, starting enrollment in Europe in Q1 2025. […]

EMBL scientists discover that an FDA-approved, over-the-counter cough syrup ingredient has potential to treat fibrotic lung disease. Summary A common over-the-counter ingredient in many cough syrups may have a greater purpose for people suffering from lung fibrosis that is related to any number of serious health conditions.  Scientists from EMBL Heidelberg were part of a […]

Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers at 13 clinics in Germany, Switzerland, the Czech Republic and Spain have investigated this with promising results. For the first time, it was possible to identify patient groups that displayed a clinically relevant treatment effect. A follow-up study will start in December […]

Being overweight increases the risk of bowel cancer. The extent of this preventable risk factor has been significantly underestimated to date. Researchers at the German Cancer Research Center (DKFZ) have now reanalyzed a large pool of data and come to the conclusion that obesity is responsible for over 20 percent of bowel cancer cases. More […]

Victoria Stodden, statistician and associate professor at the Daniel J. Epstein Department of Industrial and Systems Engineering at the University of Southern California, has been selected to receive a prestigious Humboldt Research Award. Granted by the Alexander von Humboldt Foundation, the award is bestowed on internationally leading researchers in recognition of outstanding academic achievements. A […]

EMBL’s scientists have been instrumental in helping the world understand, decode, archive, and manipulate genomes at scale and across many branches of the evolutionary tree By Ewan Birney, Eileen Furlong, and Arnaud Krebs In 1978, British biochemist Frederick Sanger’s team released the genome sequence of ϕX174 – a virus that infects bacteria. The sequence – the […]

Researchers developed a microscope made to travel – miniature in scale, fast in imaging samples, and giant in resolution. Microscopy allows us to see the unknown, solve mysteries, and advance knowledge. When EMBL scientists were looking to take the organisation’s world-class advanced microscopy from the lab to the field, as part of the Traversing European Coastlines […]

From January 1, 2025, Roman Sarott and his research group “Chemically Induced Proximity” will develop small molecules with special function: they are designed to induce new interactions between proteins in order to reprogram cellular signaling pathways and thereby open up new therapeutic possibilities. “I am very much looking forward to my new role at the […]