Network News

Extraordinary funding from the Chan Zuckerberg Initiative supports two large collaborative projects that will boost imaging technology development By Stephanie Alexander, EMBL Imaging Centre Research & Service Coordinator Developing advanced imaging technologies is critical to advancing life sciences research. It is especially important to explore the detailed structure and function of tissues, cells, and macromolecules […]

Scientists at EMBL and DKFZ have discovered how cells in the liver maintain their identity and avoid becoming tumour cells Summary A collaboration between EMBL Heidelberg and the German Cancer Research Centre (DKFZ) led to the identification of a special protein in liver cells, which helps maintain the cells’ identity throughout their lifetime and prevents […]

A combination of new laboratory technology and artificial intelligence is set to make the rapid and precise differentiation of subgroups of brain tumours widely available. An international research group led by Professor Dr. Dr. Felix Sahm from the Department of Neuropathology at Heidelberg University Hospital and the Heidelberg Faculty of Medicine at Heidelberg University is […]

A research team from the Heidelberg Medical Faculty, the German Cancer Research Center (DKFZ), the Berlin Institute of Health at Charité (BIH) and the Max Delbrück Center has discovered new details about the spread of the incurable bone marrow cancer “multiple myeloma” in the body: When the cancer cells break out of the bone and […]

New evidence points towards a forceful entry of HIV-1 capsid into the nucleus of human cells Researchers at the Max Planck Institute of Biophysics and Heidelberg University have observed largely intact HIV-1 capsids as they enter the cell nucleus through specialized channels called nuclear pores. In an exciting interdisciplinary study, they propose a new mechanism […]

Using a new method to study how carbohydrates modify proteins, scientists have discovered that gut bacteria can alter molecular signatures in the brain Summary Our guts are home to trillions of bacteria, and research over the last few decades has established how essential they are to our physiology – in health and disease. A new study […]

Structural biologists provide a first-time look at the atomic level into the quality control mechanism of this complex molecular machine A complex molecular machine, the spliceosome, ensures that the genetic information from the genome, after being transcribed into mRNA precursors, is correctly assembled into mature mRNA. Splicing is a basic requirement for producing proteins that […]

Approval based on positive results from Phase III ATTRibute-CM study / Beyonttra™ is a near-complete (≥90%) stabilizer of transthyretin (TTR) minimizing amyloid formation / Phase III ATTRibute-CM study with Beyonttra™ has shown clear benefits on cardiovascular endpoints already starting as early as 3 months after treatment initiation. Berlin, February 11, 2025 – The European Commission has […]

Researchers of the Heidelberg University, Heidelberg University Hospital (UKHD) and Heidelberg Institute for Theoretical Studies (HITS) have developed a synthetic peptide based on the natural protein S100A1, a nearly universal “fuel” for weakened hearts. The researchers combined computer-aided methods with lab studies to investigate the therapeutic effect of the so called S100A1ct peptide molecule. The […]