Research
New study points to stem cell-like cells as the origin of persistent disease and relapses New fundamental research could help combat treatment-resistant leukaemia and prevent relapses in children and adolescents. A group of scientists studied a certain type of leukaemia and identified individual stem cell-like cells responsible for relapses in kids. They have also precisely […]
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Playing Dominos: How an Artificial Protein Emerges from Fitting Together Individual Components
Heidelberg scientists develop AI model for producing new molecular machines in a targeted way The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of […]
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Even more precise prostate biopsy thanks to micro-ultrasound
The team at Heidelberg University Hospital’s Department of Urology, led by its new Medical Director Professor Johannes Huber, has introduced a new imaging technique called micro-ultrasound to assist with prostate biopsies in Heidelberg. This technique allows even the smallest tissue abnormalities to be targeted with great precision. Another advantage for patients is that magnetic resonance […]
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European Commission Grants Approval of Ogsiveo
Merck announced that the European Commission granted approval for Ogsiveo for the treatment of adults with desmoid tumors. 18 Aug 2025 | Darmstadt, Germany Merck, a leading science and technology company, announced today that the European Commission (EC) granted marketing authorization for OGSIVEO® (nirogacestat), an oral gamma secretase inhibitor, as monotherapy for the treatment of adults with progressing […]
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Freezing brain tumor cells in a dormant state
Every brain tumor is made up of cells in successive stages of activation. Researchers at the German Cancer Research Center (DKFZ) and Heidelberg University have now analyzed the individual structure of these activation pyramids in malignant brain tumors for the first time. In doing so, they discovered a signaling protein that slows down the transition […]
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1.2 million euros in funding for the production of “gene taxis”
The Dietmar Hopp Foundation is supporting the establishment of an experimental production unit for gene therapies for the heart at Heidelberg University’s Medical Faculty, in the Department of Cardiology, Angiology, and Pneumology at Heidelberg University Hospital (UKHD). The new production capacities for therapeutic viruses, the “gene taxis” to the diseased heart, strengthen the pioneering role […]
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New Member: Welcome in our cluster to Fab’ulous SAS
Fabulous accelerates antibody discovery with a fully computational, AI-powered approach that delivers preclinical ready human antibodies in just 3–5 days. Starting from your scientific problem, it designs candidates using curated human sequence data and in silico maturation to mimic natural immune evolution. This process enhances affinity, thermostability, and expression while reducing off-target binding. Each sequence […]
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AGC Biologics’ Heidelberg Site Supplies Drug Substance for Phase II Studies of Valneva’s Tetravalent Shigella Vaccine Candidate
SEATTLE AND HEIDELBERG – July 29, 2025 – AGC Biologics, your friendly CDMO expert, today announced a development and manufacturing services agreement with specialty vaccine company Valneva SE (Nasdaq: VALN; Euronext Paris: VLA) to supply drug substance for an investigational four-valent Shigella bioconjugate vaccine at the CDMO’s Heidelberg facility. Valneva exclusively licensed the vaccine candidate from LimmaTech Biologics AG, which […]
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From bench to code: collaboration unlocks insights into Alzheimer’s disease
How a chance encounter at a scientific conference resulted in a fruitful cross-Atlantic research collaboration In 2023, EMBL-EBI Postdoctoral Fellow Iguaracy Pinheiro de Sousa presented his bioinformatics work on how cells communicate within the heart, as part of the Network Biology meeting in Cold Spring Harbour, New York. “I met Yifei Cai during the opening […]
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