Research
EMBL scientists discover that an FDA-approved, over-the-counter cough syrup ingredient has potential to treat fibrotic lung disease. Summary A common over-the-counter ingredient in many cough syrups may have a greater purpose for people suffering from lung fibrosis that is related to any number of serious health conditions. Scientists from EMBL Heidelberg were part of a […]
read moreAntibody that Neutralizes Inhibitory Factors Involved in Nerve Regeneration Leads to Enhanced Motor Function after Acute Spinal Cord Injury
Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers at 13 clinics in Germany, Switzerland, the Czech Republic and Spain have investigated this with promising results. For the first time, it was possible to identify patient groups that displayed a clinically relevant treatment effect. A follow-up study will start in December […]
read moreColorectal cancer: role of obesity underestimated to date
Being overweight increases the risk of bowel cancer. The extent of this preventable risk factor has been significantly underestimated to date. Researchers at the German Cancer Research Center (DKFZ) have now reanalyzed a large pool of data and come to the conclusion that obesity is responsible for over 20 percent of bowel cancer cases. More […]
read moreA new EMBL microscope hits the road
Researchers developed a microscope made to travel – miniature in scale, fast in imaging samples, and giant in resolution. Microscopy allows us to see the unknown, solve mysteries, and advance knowledge. When EMBL scientists were looking to take the organisation’s world-class advanced microscopy from the lab to the field, as part of the Traversing European Coastlines […]
read moreSchizophrenia: NMI observes processes in nerve cells
Is it enough to treat the symptoms, or would we rather get to the causes of the illness? Up to now, schizophrenia has mainly been treated symptomatically, as little is known about the exact underlying processes. Researchers at the NMI Natural and Medical Sciences Institute in Reutlingen have succeeded in gaining a better understanding of […]
read moreBrain tumour cells rapidly integrate into brain-wide neuronal circuits
Researchers at the Medical Faculty of Heidelberg University and the Heidelberg University Hospital have used modified rabies viruses to label glioblastoma tumour cells and their direct cell contacts in the mouse brain. The new method showed that the tumour cells are connected to different types of nerve cells throughout the entire brain at a very […]
read moreWarm – warmer – neuronal rapid fire: How the brain gets used to heat
For the first time, researchers from the Heidelberg Medical Faculty of the Heidelberg University describe a cell-specific neuronal mechanism associated with heat tolerance in the journal Nature Neuroscience. Animals and humans develop a certain tolerance to prolonged heat: the body adjusts to release heat instead of generating it, and the metabolism and cardiovascular system adapt. […]
read moreFrom snapshots to motion: watching biology in action
With a novel approach, EMBL scientists discovered important interactions between molecular machines, potentially offering new opportunities for drug development Summary Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For […]
read moreChromosomal chaos promotes therapy resistance in leukemia cells and opens up new treatment approaches
Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM* and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular […]
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