Research

A research team including scientists from Heidelberg University Hospital has gained new insights into HIV-1. Researchers from Martinsried, Heidelberg und Yale have discovered the mechanism behind an important step in the life cycle of HIV. Working together with teams at Heidelberg and Yale Universities, they found that the enigmatic “spacer peptide 2”, one of the […]

Using a new combination of three sensors and artificial intelligence, researchers at Heidelberg Medical Faculty of Heidelberg University and Heidelberg University Hospital are recognising patterns in babies’ movements that show whether their nervous system is developing healthily. The way an infant moves spontaneously in the first few months of life can indicate whether its nervous system […]

New EMBL-EBI project explores the use of a concept developed in aerospace engineering to support rare disease research, diagnosis, and treatment Rare diseases are individually uncommon, but together they affect over 300 million people worldwide. There are more than 7,000 conditions that are classed as rare diseases, and many of them don’t have approved treatments. […]

Researchers led by Dr. Michael Pawlak from NMI Technologie Transfer GmbH (NMI TT) in Reutlingen and Prof. Dr. Hans Neubauer from the Women’s Hospital at the University of Düsseldorf have developed a new method that enables a more precise analysis of individual tumor cells circulating in the blood. This allows not only the previously possible […]

Müller, E.; Enzlein, T.; Niemeyer, D.; von Ammon, L.; Stumpo, K.; Biber, K.; Klein, C.; Hopf, C. Exploring the Aβ Plaque Microenvironment in Alzheimer’s Disease Model Mice by Multimodal Lipid-Protein-Histology Imaging on a Benchtop Mass Spectrometer. Pharmaceuticals 2025, 18, 252. https://doi.org/10.3390/ph18020252 Abstract Amyloid-β (Aβ) plaque deposits in the brain are a hallmark of Alzheimer’s disease (AD) neuropathology. Plaques […]

Researchers have increased the resolution in fluorescence microscopy by a factor of 30 without having to sequentially switch fluorescent molecules between light and dark states. The Nobel Prize-winning STED and PALM/STORM microscopes, as well as other super-resolution fluorescence microscopes, provide resolutions of a fraction of the wavelength of light. However, to image adjacent fluorescent molecules […]

The results from a phase 3 trial involving 662 patients from 67 clinics led by Heidelberg University Hospital and the Heidelberg Medical Faculty at Heidelberg University indicate that a new immunotherapeutic approach keeps the disease under control for longer. The data has just been published in the Journal of Clinical Oncology. The study has been […]

Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the stomach, where they block acid production. Researchers at the German Cancer Research Center (DKFZ) made the surprising discovery that zinc-carrying proteins, which are found in all […]

Scientists at EMBL and DKFZ have discovered how cells in the liver maintain their identity and avoid becoming tumour cells Summary A collaboration between EMBL Heidelberg and the German Cancer Research Centre (DKFZ) led to the identification of a special protein in liver cells, which helps maintain the cells’ identity throughout their lifetime and prevents […]