Research

The Earth BioGenome Project is accelerating its efforts tenfold to sequence all life on Earth by 2035 Summary A global collaboration that includes experts at EMBL’s European Bioinformatics Institute (EMBL-EBI) has entered the second phase of its ambitious plan to sequence all 1.67 million known species on Earth by 2035.  The Earth BioGenome Project (EBP), a […]

Alumnus Bastian Linder discusses the origin of this start-up and how a tRNA mechanism is helping scientists understand the importance and use of various RNA modifications as they pertain to disease. With just two dots above a letter, the German umlaut can instantly change a word’s pronunciation, its quantity (singular to plural), or even its […]

Chordomas are rare bone tumors for which there are currently no effective drugs. A research team from the German Cancer Research Center (DKFZ) and the National Center for Tumor Diseases (NCT) Heidelberg has now developed a promising approach: Tailor-made mini-proteins specifically block the central driver of tumor development. In the result, they slowed the growth […]

Researchers from the German Cancer Research Center (DKFZ) have collaborated with the SILVACX project group at Heidelberg University to develop a therapeutic vaccination concept that can mobilize the immune system to target cancer cells. The team showed that virus peptides coupled to silica nanoparticles can elicit effective T-cell responses against HPV-related tumors. In a mouse […]

Researchers identify neurotoxic protein complex – Pharmacological inhibitor opens up new perspectives for the development of effective therapies A molecular mechanism that significantly contributes to the progression of Alzheimer’s disease has been discovered by a research team led by neurobiologist Prof. Dr Hilmar Bading of Heidelberg University. In joint experiments with researchers from Shandong University […]

A team of scientists from the German Cancer Research Center (DKFZ) and the Netherlands Cancer Institute has discovered a previously unknown vulnerability in cancer cells: When cell division is blocked with chemotherapeutic agents such as Taxol, cancer cells produce small immunogenic peptides that could open up new avenues for immune-based cancer therapies. Frequent cell division […]

Key Milestone for PL BioScience as new headquarters are announced PL BioScience announced the next major step in its expansion – an upcoming move to a new 1,200 m² facility in Aachen, in September 2025. This key milestone will support the company’s growth and upscaling efforts, and provide the world’s largest HPL output, with 20,000L […]

New study points to stem cell-like cells as the origin of persistent disease and relapses New fundamental research could help combat treatment-resistant leukaemia and prevent relapses in children and adolescents. A group of scientists studied a certain type of leukaemia and identified individual stem cell-like cells responsible for relapses in kids. They have also precisely […]

Heidelberg scientists develop AI model for producing new molecular machines in a targeted way The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of […]