Research

Abstract Objectives:  To investigate the proteomic profile of different molecular subtypes of pancreatic ductal adenocarcinoma (PDAC) and understand their impact on patient outcomes, particularly focusing on pathways involved in xenobiotic metabolism and drug resistance. Methods:  The study utilized the serum-free PACO cell culture model and a quantitative prefractionation-based MALDI/MS approach to establish the proteomic profiles […]

Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer patients. Painkillers such as diclofenac and paracetamol are among the most commonly used drugs worldwide. They relieve pain and inflammation […]

Full text in German below. Merck und Promega arbeiten gemeinsam an 3D-Zelltechnologie für die Wirkstoffforschung Strategische Partnerschaft bündelt Know-how von Merck im Bereich Organoide mit Promegas Assay-TechnologienForschende erhalten besseren und schnelleren Zugang zu krankheitsrelevanten ZellmodellenStärkt Mercks Position bei zukunftsweisenden Tools und Lösungen auf dem Gebiet der Biologie Darmstadt, Deutschland. (06. November 2025) Merck, ein führendes Wissenschafts- […]

EMBL researchers have been using a powerful technique called expansion microscopy to peek deeper inside living organisms and understand how they function One day in 2020, in the middle of the COVID-19 pandemic, EMBL Group Leader Gautam Dey received a Zoom call from his collaborator and fellow cell biologist Omaya Dudin. Dudin, who led a research group at […]

EMBL scientists improve a protein analysis technique, significantly expanding its use and making it 100 times faster – a development that could accelerate drug discovery and fundamental biological research Summary Swedish chemist Jöns Jacob Berzelius, in a letter to a fellow chemist, first suggested the name ‘proteins’ for a particular class of biological substances, deriving […]

EMBL researchers have developed a new AI tool, which, through a game of molecular laser tag, identifies cells that can shed light on the earliest origins of cancer Summary The human body relies on precise genetic instructions to function, and cancer begins when these instructions get scrambled. When cells accumulate genetic errors over time, they […]

Heidelberg researchers identify local outbreak indicators and develop new regional modeling approach Local factors such as seasonal temperature, the year-dependent water and vegetation index, and data on animal density can be used to predict regional outbreaks of avian flu in Europe. This is the finding of a research team led by epidemiologist, mathematician, and statistician […]

Philipp Uhl awarded for his work on new pharmaceutical forms and overcoming antibiotic resistance For his outstanding work in the field of pharmaceutical research, Junior Professor Dr Philipp Uhl has received the PHOENIX Pharmaceutical Science Award in the “Pharmaceutical Technology” category. Endowed with 10,000 euros per category, this prize is awarded annually by the Phoenix […]

A new method for building growth charts for children with rare diseases is being integrated into DECIPHER to help clinicians and families understand child development Summary Growth charts – used to track a child’s height and weight over time – help identify when a child’s growth is within a healthy range. But for children with […]