Research
Key Milestone for PL BioScience as new headquarters are announced PL BioScience announced the next major step in its expansion – an upcoming move to a new 1,200 m² facility in Aachen, in September 2025. This key milestone will support the company’s growth and upscaling efforts, and provide the world’s largest HPL output, with 20,000L […]
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Finding a clue to the origin of treatment-resistant leukaemia in kids
New study points to stem cell-like cells as the origin of persistent disease and relapses New fundamental research could help combat treatment-resistant leukaemia and prevent relapses in children and adolescents. A group of scientists studied a certain type of leukaemia and identified individual stem cell-like cells responsible for relapses in kids. They have also precisely […]
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Playing Dominos: How an Artificial Protein Emerges from Fitting Together Individual Components
Heidelberg scientists develop AI model for producing new molecular machines in a targeted way The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of […]
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Even more precise prostate biopsy thanks to micro-ultrasound
The team at Heidelberg University Hospital’s Department of Urology, led by its new Medical Director Professor Johannes Huber, has introduced a new imaging technique called micro-ultrasound to assist with prostate biopsies in Heidelberg. This technique allows even the smallest tissue abnormalities to be targeted with great precision. Another advantage for patients is that magnetic resonance […]
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Freezing brain tumor cells in a dormant state
Every brain tumor is made up of cells in successive stages of activation. Researchers at the German Cancer Research Center (DKFZ) and Heidelberg University have now analyzed the individual structure of these activation pyramids in malignant brain tumors for the first time. In doing so, they discovered a signaling protein that slows down the transition […]
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FOXP1 syndrome: Potential therapeutic approach discovered for rare language development disorder
FOXP1 syndrome is a congenital disorder in which the brain development of affected children is severely impaired due to a genetic variant. To date, there are no treatments that target the root cause of the disorder. A research team from the Medical Faculty Heidelberg at Heidelberg University has now demonstrated in mice, that the inhibition […]
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Possible target for new immunotherapy
A research team led by the German Cancer Research Center (DKFZ) and the Luxembourg Institute of Health has found a key mechanism that weakens the immune system in chronic lymphocytic leukemia (CLL). The scientists were able to show that the protein galectin-9 plays a key role in blocking the function of T cells, which are […]
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Beyond 1000 genomes: going deeper and wider
Ten years after the end of the 1000 Genomes Project, brand new insights emerge from its sample set, providing a more complete view of human genetic variation than ever before Summary Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful […]
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The origin of evil: stem cell-like cells are the reason for relapses of blood cancer in children and adolescents
Stem cell-like leukemia cells are responsible for relapses in children and adolescents with a certain type of blood cancer, T-ALL. Researchers at the Hopp Children’s Cancer Center Heidelberg (KiTZ), the Molecular Medicine Partnership Unit (MMPU) – an inter-institutional partnership between the European Molecular Biology Laboratory (EMBL) and the Medical Faculty of Heidelberg University – and […]
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