Research

An international team, including researchers from Heidelberg University’s Faculty of Medicine and Heidelberg University Hospital, has developed the PANGEA-SMM prognostic tool. This tool makes it possible to determine with greater accuracy than before whether a precancerous condition—known as “smoldering multiple myeloma”—is progressing and thus requires treatment. The free online tool for treatment teams is available […]

International research team under Heidelberg supervision examines role of NAC complex in essential process of protein folding In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps towards folding proteins into their correct three-dimensional structures. This discovery was made by an international research team […]

For the first time, researchers have succeeded in mapping the organization of immune cells in human lymph nodes. The study was led by scientists from Heinrich Heine University Düsseldorf, Düsseldorf University Hospital, the German Cancer Research Center (DKFZ), the European Molecular Biology Laboratory (EMBL), and the Max Delbrück Center (MDC) in Berlin. They were able […]

In ovarian cancer, immunotherapies using checkpoint inhibitors have so far been effective in only a small number of patients. Researchers at the Helmholtz Institute for Translational Oncology (HI-TRON Mainz*) have now discovered that lipid metabolism processes in the tumor microenvironment play a decisive role in how well such therapies work. The findings open up new […]

The goal of “KIRR Real: Real-World Lab for Legally Compliant AI and Robotics,” a joint initiative by Fraunhofer IPA and ARENA2036, was to support companies in Baden-Württemberg in implementing the EU AI Act and the EU Machinery Directive, which will take effect in 2027. The results of the collaboration with 15 companies have now been […]

How can the risk of failure in the development of drug compounds be reduced? In a recent paper, researchers at the NMI present a newly developed framework that makes the development of drug compounds from so-called single-domain antibodies (sdAb) safer and more reliable. Until now, drug development has generally proceeded as follows: one starts with […]

The Hector Foundation is providing €1.3 million in funding for an interdisciplinary research project investigating the cardiological side effects of checkpoint inhibitors. The consortium, with partners at Heidelberg University’s Medical Faculty, the German Cancer Research Center, the Max Delbrück Center in Berlin, and the University Medical Center Schleswig-Holstein in Kiel, is investigating why these cancer […]

The introduction of mammography screening programs in Europe has significantly changed breast cancer diagnoses, accompanied by a decline in breast cancer mortality rates. This is shown by one of the most comprehensive analyses of population-based data on breast cancer in 21 European countries to date, led by the German Cancer Research Center (DKFZ). The most […]

How can the risk of failure in the development of drug compounds be reduced? In a recent paper, researchers at the NMI present a newly developed framework that makes the development of drug compounds from so-called single-domain antibodies (sdAb) safer and more reliable. Until now, drug development has generally proceeded as follows: one starts with […]