Research

Heidelberg scientists develop AI model for producing new molecular machines in a targeted way The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of […]

The team at Heidelberg University Hospital’s Department of Urology, led by its new Medical Director Professor Johannes Huber, has introduced a new imaging technique called micro-ultrasound to assist with prostate biopsies in Heidelberg. This technique allows even the smallest tissue abnormalities to be targeted with great precision. Another advantage for patients is that magnetic resonance […]

Every brain tumor is made up of cells in successive stages of activation. Researchers at the German Cancer Research Center (DKFZ) and Heidelberg University have now analyzed the individual structure of these activation pyramids in malignant brain tumors for the first time. In doing so, they discovered a signaling protein that slows down the transition […]

FOXP1 syndrome is a congenital disorder in which the brain development of affected children is severely impaired due to a genetic variant. To date, there are no treatments that target the root cause of the disorder. A research team from the Medical Faculty Heidelberg at Heidelberg University has now demonstrated in mice, that the inhibition […]

A research team led by the German Cancer Research Center (DKFZ) and the Luxembourg Institute of Health has found a key mechanism that weakens the immune system in chronic lymphocytic leukemia (CLL). The scientists were able to show that the protein galectin-9 plays a key role in blocking the function of T cells, which are […]

Ten years after the end of the 1000 Genomes Project, brand new insights emerge from its sample set, providing a more complete view of human genetic variation than ever before Summary Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful […]

Stem cell-like leukemia cells are responsible for relapses in children and adolescents with a certain type of blood cancer, T-ALL. Researchers at the Hopp Children’s Cancer Center Heidelberg (KiTZ), the Molecular Medicine Partnership Unit (MMPU) – an inter-institutional partnership between the European Molecular Biology Laboratory (EMBL) and the Medical Faculty of Heidelberg University – and […]

Diabetics have a higher risk of colorectal cancer and often a poorer prognosis after developing the disease. The biological mechanisms behind this association were largely unknown. A research team at the German Cancer Research Center (DKFZ) has now discovered that tumors with a low number of immune cells appear to be particularly susceptible to the […]

Sepsis is one of the most dangerous medical emergencies. The condition is the result of a misdirected immune response to an infection, which can quickly lead to organ failure and death. Every hour counts – but early detection is difficult in clinical practice. A new study from Heidelberg now presents an innovative approach: artificial intelligence […]