
Research

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM* and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular […]
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bioRN annual report 2024

Selenium proteins as a possible new target for cancer research
An important enzyme helps the body produce selenium proteins – this discovery could open up new strategies for treating cancer in children. This has been published by scientists from the University of Würzburg, the University Sao Paolo, the German Cancer Research Center (DKFZ) and the Heidelberg Stem Cell Institute HI-STEM*. Proteins containing the element selenium […]
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Microbial load can influence disease associations
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations Summary In sickness or in health, the billions of microorganisms that inhabit our guts are our constant companions throughout life. […]
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New findings on cell types and their interactions in multiple sclerosis
An international research team led by Professor Dr. Lucas Schirmer and Professor Dr. Julio Saez-Rodriguez from the Medical Faculties of Heidelberg University, in Mannheim and Heidelberg, has studied the different cell types in so-called subcortical lesions, tissue damage to deep brain structures, at different stages of multiple sclerosis (MS) and investigated how they communicate. In […]
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Award-winning research in emergency medicine in Heidelberg
Research is constantly being conducted at Heidelberg University Hospital to continuously improve patient care and patient safety. The emergency medicine department has already received several awards for its innovations and improvements. The Emergency Medicine Section of the Department of Anesthesiology at Heidelberg University Hospital (UKHD) recently received the Rudolf Frey Prize 2024 from the German […]
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Digital Self-Help Programs Support the Treatment of Eating Disorders
Heidelberg studies: online interventions might bridge healthcare gaps Digital self-help programs for adults with eating disorders may contribute to significantly reducing the symptoms in affected individuals. That is shown by two studies on binge eating and bulimia nervosa conducted by scientists at Heidelberg University. The Research Unit Clinical Psychology and Psychotherapy tested the potential of […]
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The cellular superhero that protects us against RNA viruses
Scientists have discovered how the antiviral protein TRIM25 finds and binds viral RNA to activate an immune response Summary Every second of every day, our body is under attack. The invading agents are viruses, bacteria, parasites, toxins – living and non-living entities that might negatively impact our body’s functioning. What keeps us safe is a […]
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How do rare genetic variants affect health? AI provides more accurate predictions
Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome. However, particularly in the case of genetic variants that only rarely occur in the population, the influence on the presentation of certain pathological traits has so far been difficult to determine. Researchers from the German Cancer […]
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