Research

Researchers identify neurotoxic protein complex – Pharmacological inhibitor opens up new perspectives for the development of effective therapies A molecular mechanism that significantly contributes to the progression of Alzheimer’s disease has been discovered by a research team led by neurobiologist Prof. Dr Hilmar Bading of Heidelberg University. In joint experiments with researchers from Shandong University […]

A team of scientists from the German Cancer Research Center (DKFZ) and the Netherlands Cancer Institute has discovered a previously unknown vulnerability in cancer cells: When cell division is blocked with chemotherapeutic agents such as Taxol, cancer cells produce small immunogenic peptides that could open up new avenues for immune-based cancer therapies. Frequent cell division […]

New study points to stem cell-like cells as the origin of persistent disease and relapses New fundamental research could help combat treatment-resistant leukaemia and prevent relapses in children and adolescents. A group of scientists studied a certain type of leukaemia and identified individual stem cell-like cells responsible for relapses in kids. They have also precisely […]

Heidelberg scientists develop AI model for producing new molecular machines in a targeted way The targeted engineering of artificial proteins with unique properties – that is possible with the assistance of a novel method developed by a research team led by Prof. Dr Dominik Niopek at the Institute of Pharmacy and Molecular Biotechnology (IPMB) of […]

The team at Heidelberg University Hospital’s Department of Urology, led by its new Medical Director Professor Johannes Huber, has introduced a new imaging technique called micro-ultrasound to assist with prostate biopsies in Heidelberg. This technique allows even the smallest tissue abnormalities to be targeted with great precision. Another advantage for patients is that magnetic resonance […]

Every brain tumor is made up of cells in successive stages of activation. Researchers at the German Cancer Research Center (DKFZ) and Heidelberg University have now analyzed the individual structure of these activation pyramids in malignant brain tumors for the first time. In doing so, they discovered a signaling protein that slows down the transition […]

FOXP1 syndrome is a congenital disorder in which the brain development of affected children is severely impaired due to a genetic variant. To date, there are no treatments that target the root cause of the disorder. A research team from the Medical Faculty Heidelberg at Heidelberg University has now demonstrated in mice, that the inhibition […]

A research team led by the German Cancer Research Center (DKFZ) and the Luxembourg Institute of Health has found a key mechanism that weakens the immune system in chronic lymphocytic leukemia (CLL). The scientists were able to show that the protein galectin-9 plays a key role in blocking the function of T cells, which are […]

Ten years after the end of the 1000 Genomes Project, brand new insights emerge from its sample set, providing a more complete view of human genetic variation than ever before Summary Completed in 2003, the Human Genome Project gave us the first sequence of the human genome, albeit based on DNA from a small handful […]