Research

Researchers from Heidelberg University’s Faculty of Medicine and the Technical University of Munich have investigated the genetic activity of “budding” head and neck carcinomas. In the “buds”—clusters of cells that detach from the tumor and are associated with a poor prognosis—they found a characteristic pattern of gene activity. This marker signature provides insights into the […]

MGnify Genomes offers new ways to explore microbial communities in soil, marine sediments, and the gut If you could shrink yourself to the size of a microbe, you would discover that every handful of soil and every bucket of seawater is akin to a bustling city filled with millions of microbes. Until recently, most of […]

The bioprocess experts from BioThrust Yasemin van Heuvel, Valentin von Werz and the group of Oliver Spadiut at Technische Universität Wien and the team at SimVantage released this publication on NK-92 cell manufacturing. The team collaborated to compare our ComfyCell bioreactor with a conventional pitched-blade stirred-tank bioreactor (2 L scale). While both systems supported comparable […]

A novel developed biomimetic tissue substitute combines precisely tunable mechanical properties with biological functionality and is now ready for applications in medical technology. The material was developed in the »PolyKARD« project by the Fraunhofer Institute for Applied Polymer Research IAP and the NMI Natural and Medical Sciences Institute. From April 20 to 24, 2026, the […]

Not only actual chronological age, but also individual aging at the molecular level is a key factor in the development of cancer. This was discovered by scientists at the German Cancer Research Center (DKFZ) and the Saarland Cancer Registry. If the so-called “epigenetic clocks” indicate accelerated biological aging, the likelihood of a cancer diagnosis increases. […]

Nagel, A.; Hass, E.W.; Hayes, H.; Huelbes, L.; Oliveira, S.; Hardin, H.M.; Marasigan, M.; Nisenbaum, E.; Misztal, C.; Telischi, F.F.; et al. Fimepinostat Promotes Apoptosis and Decreases Cytokine Secretion in NF2-Related Human Schwannoma Cells. Int. J. Mol. Sci. 2026, 27, 2636. https://doi.org/10.3390/ijms27062636 https://www.mdpi.com/1422-0067/27/6/2636 Simple Summary This study focuses on the action of fimepinostat, a dual histone deacetylase (HDAC)/phosphosphoinositide-3 kinase […]

Successful pilot project at Heidelberg University Hospital Regularly surveying patients about their health-related quality of life is a key aspect of patient-centred medicine. At Heidelberg University Hospital, a new digital system is being used for this purpose in a pilot project: patients complete online questionnaires on their own mobile devices, after which the data is […]

We are very proud to be a part of a joint, international effort to develop a genetically engineered mouse model (GEMM) for the understudied pediatric cancer, alveolar rhabdomyosarcoma (aRMS). This model, which has been deposited at JAX (strain 041178), will accelerate the development of living-saving therapies for children with aRMS. This model was developed as a […]

Excessive fertilization in agriculture weakens crops, threatens drinking water quality, and harms the soil. Researchers at the Fraunhofer Institute for Interfacial Engineering and Biotechnology IGB are now developing an alternative fertilizer that is fully biodegradable, supplies plants exclusively with the nutrients they need, and prevents over-fertilization. More information in German below: Jahr für Jahr werden […]