
Research

Interdisciplinary research team uses DNA microbeads to control the development of cultivated tissue A new molecular engineering technique can precisely influence the development of organoids. Microbeads made of specifically folded DNA are used to release growth factors or other signal molecules inside the tissue structures. This gives rise to considerably more complex organoids that imitate […]
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“Structurally” sound
Connecting structure to function in five decades of research By Julia Mahamid, Kristina Djinovic-Carugo, Janet Thornton Structural biology investigates the three-dimensional structure of biological molecules, such as proteins and nucleic acids, and tries to understand their function through this lens. The journey of structural biology in the last five decades has been one of continuous […]
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Cystic fibrosis research: Improving therapy with CFTR modulators using short-chain fatty acids
The German Cystic Fibrosis Association (Bundesverband Mukoviszidose e.V.) is providing 148,330 euros to fund a project by Dr. Andrew Tony-Odigie’s working group (Heidelberg University Hospital) on the use of commensal (beneficial) bacteria and their metabolic products to improve therapy with CFTR modulators. The scientists are investigating previously unknown interactions between modulator therapy and commensals and […]
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