Our latest news

Novel capsid technology to enable convenient delivery in the doctor’s office of IKAR-003 for intermediate AMD, designed to prevent progression to sight-threatening disease NORWICH, UK & CHICAGO, US, January 6 2026 – Ikarovec Ltd, which is developing dual-pathway gene therapies for vision-threatening retinal diseases, and VectorBuilder, a global leader in gene delivery technologies, have entered into an exclusive […]

A new single-cell map reveals how human reproductive organs form and respond to environmental influences New research has mapped the cell types that specialise to form reproductive organs in both sexes, identifying key genes and signals that drive this process. The findings offer important insights into conditions affecting the reproductive organs and how environmental chemicals […]

Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), HI-STEM*, and the Broad Institute have demonstrated that this is possible with an innovative approach. In a study now published in Nature, the team showed that mRNA technology can be used to transform the liver in mice […]

Sanofi’s Wayrilz approved in the EU as the first BTK inhibitor to treat immune thrombocytopenia Paris, December 23, 2025 – The European Commission has approved Wayrilz (rilzabrutinib), a novel, oral, reversible, Bruton’s tyrosine kinase (BTK) inhibitor, as a new treatment for immune thrombocytopenia (ITP) in adult patients who are refractory to other treatments. This follows the positive opinion by […]

Sanofi to acquire Dynavax, adding a marketed adult hepatitis B vaccine and phase 1/2 shingles candidate to the pipeline Paris, December 24, 2025. Sanofi announced today that it has entered into an agreement to acquire Dynavax Technologies Corporation (Dynavax), a publicly traded vaccines company with a marketed adult hepatitis B vaccine (HEPLISAV-B®) and differentiated shingles vaccine […]

S. A. Iakab, J. Cordes, T. Enzlein, et al. “ From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models.” Adv. Sci. (2025): e16098. https://doi.org/10.1002/advs.202516098 Abstract Human 3D cell cultures, including spheroids and organoids, are essential biological models for translational pharmaceutical and biomedical research. However, their 3D analysis […]

Role of neural cells in tumor progression is becoming ever more evident. HI-STEM scientists published a landmark study in Nature elucidating the role of neural innervation in promoting the tumor progression in pancreatic cancer and how this cross-talk works. Now this study has been featured in an Outlook article in Nature Magazine. Full article can be […]

Full text in German below. Eine Studie stellt die molekulare Verbindung zwischen Tumorstoffwechsel und Wirkstoffbindung in Krebszellen her Madison, WI USA. (09. Dezember 2025) Eine neue Studie, veröffentlicht in Nature Communications, zeigt technologische Vorteile, die Durchbrüche in der Präzisionsmedizin beschleunigen. Durchgeführt wurde sie als Zusammenarbeit zwischen Promega, dem Center for Advanced Study of Drug Action an der […]

Revealing a new layer in lung cancer diagnostics using direct RNA sequencing HEIDELBERG, Germany, December 16, 2025 – Hummingbird Diagnostics GmbH, a pioneer in harnessing blood-based small RNAs for early disease detection and characterization, today announced the publication of a new study in Nature Communications Medicine introducing an Oxford Nanopore Technologies (ONT)-based method for detecting small RNA […]