Research
Researchers at the Medical Faculty of Heidelberg University and the Heidelberg University Hospital have used modified rabies viruses to label glioblastoma tumour cells and their direct cell contacts in the mouse brain. The new method showed that the tumour cells are connected to different types of nerve cells throughout the entire brain at a very […]
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Warm – warmer – neuronal rapid fire: How the brain gets used to heat
For the first time, researchers from the Heidelberg Medical Faculty of the Heidelberg University describe a cell-specific neuronal mechanism associated with heat tolerance in the journal Nature Neuroscience. Animals and humans develop a certain tolerance to prolonged heat: the body adjusts to release heat instead of generating it, and the metabolism and cardiovascular system adapt. […]
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From snapshots to motion: watching biology in action
With a novel approach, EMBL scientists discovered important interactions between molecular machines, potentially offering new opportunities for drug development Summary Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For […]
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Chromosomal chaos promotes therapy resistance in leukemia cells and opens up new treatment approaches
Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM* and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular […]
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bioRN annual report 2024
Selenium proteins as a possible new target for cancer research
An important enzyme helps the body produce selenium proteins – this discovery could open up new strategies for treating cancer in children. This has been published by scientists from the University of Würzburg, the University Sao Paolo, the German Cancer Research Center (DKFZ) and the Heidelberg Stem Cell Institute HI-STEM*. Proteins containing the element selenium […]
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Microbial load can influence disease associations
Scientists have developed a new machine-learning model to predict microbial load — the density of microbes in our guts — and used it to demonstrate how microbial load plays an important role in disease-microbiome associations Summary In sickness or in health, the billions of microorganisms that inhabit our guts are our constant companions throughout life. […]
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New findings on cell types and their interactions in multiple sclerosis
An international research team led by Professor Dr. Lucas Schirmer and Professor Dr. Julio Saez-Rodriguez from the Medical Faculties of Heidelberg University, in Mannheim and Heidelberg, has studied the different cell types in so-called subcortical lesions, tissue damage to deep brain structures, at different stages of multiple sclerosis (MS) and investigated how they communicate. In […]
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Award-winning research in emergency medicine in Heidelberg
Research is constantly being conducted at Heidelberg University Hospital to continuously improve patient care and patient safety. The emergency medicine department has already received several awards for its innovations and improvements. The Emergency Medicine Section of the Department of Anesthesiology at Heidelberg University Hospital (UKHD) recently received the Rudolf Frey Prize 2024 from the German […]
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