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How is TR-FRET Used in Drug Discovery?

How is TR-FRET Used in Drug Discovery?

This post is Part 2 of a two-part blog series. Read part 1: What is a TR‑FRET assay and how is it used in drug discovery? In a previous blog post, we covered the fundamental principles of Time-Resolved Fluorescence (TR) Förster Resonance Energy Transfer (TR-FRET), including how long-lived lanthanide donors like europium enable high-sensitivity, “mix-and-read” assays. Because TR-FRET provides a ratiometric, proximity-based […]

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Triple ERC Success at the German Cancer Research Center

Triple ERC Success at the German Cancer Research Center

Three researchers at the German Cancer Research Center (DKFZ) have each been awarded a Starting Grant from the European Research Council (ERC) this year. Daniel Kirschenbaum, Lena Kutscher, and Michael Scherer impressed the ERC with their innovative research approaches to fundamental questions in cancer medicine. With the funding, they plan to investigate why certain brain […]

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Cancer Cachexia: How a Tumor Protein Drives Wasting in the Body

Cancer Cachexia: How a Tumor Protein Drives Wasting in the Body

Researchers at Helmholtz Munich, the Heidelberg Faculty of Medicine at Heidelberg University, the German Center for Diabetes Research (DZD) and the Technical University of Munich (TUM) have identified a previously unknown mechanism that can drive cancer cachexia – a wasting process in the body that primarily affects muscle and fat tissue. A central role is […]

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