April 22, 2024

Webinar: Advancing in vitro high-throughput transcriptomics for chemical toxicity testing

Webinar: Advancing in vitro high-throughput transcriptomics for chemical toxicity testing
About this webinar

Toxicity testing is on the cusp of transitioning away from expensive and ethically challenged animal-based methods, towards more efficient alternative approaches. Concurrently, advances in technologies that examine sub-lethal effects on gene expression have led to increased interest in the concept of transcriptomic points of departure (tPODs), or the threshold concentration beyond which a concerted response in gene expression may be expected, indicating the potential for adverse effects at the organismal level.

These concentrations have been found to be lower than (i.e. protective of) benchmark effect concentrations that can cause mortality and reproductive defects. Consequentially, there is growing scientific and regulatory interest in tPODs for applications in chemical screening and prioritization.

Hear from researchers from McGill University, as they present case studies in optimizing and advancing efficient workflows that couple in vitro exposures with ultraplexed library preparation using the QIAseq UPXome RNA Library Kit. This approach has increased the throughput of differential expression and dose-response analysis for tPODs derivation.

Additionally, learn how combining ultraplexed library preparation with mosquito® automated liquid handling has improved efficiency in two ways:

  • Shortening the overall library preparation protocol time
  • Reducing reagent usage by a half by miniaturizing protocol volumes
register now

Our latest News

discover more
SPT Labtech brings the power of miniaturization to more genomics researchers with mosquito® Gen3

SPT Labtech brings the power of miniaturization to more genomics researchers with mosquito® Gen3

This new instrument delivers automated true positive displacement technology in an exceptionally compact footprint Cambridge, UK – SPT Labtech, a global leader in the design, development and manufacture of automated instrumentation and consumables for life science applications, has expanded its nanoliter liquid handling portfolio with the launch of mosquito Gen3. As the most compact and […]

New Member: Welcome in our cluster to BioKryo GmbH

New Member: Welcome in our cluster to BioKryo GmbH

BioKryo is a biorepository focused on the storage of biological samples in temperatures ranging from -196°C in liquid nitrogen in cryotanks to -80°C, -20°C and 4°C in freezers. Their goal is to support biotechnology/pharmaceutical companies in their manufacturing process by providing a safe, redundant and qualified storage of their biological samples. Some examples of samples […]

German Biotechnology Days 2025

German Biotechnology Days 2025

BioRN will be the hosting Bioregion for the upcoming German Biotechnology Days, which will take place in Heidelberg on 9-10 April 2025. Over two days, the ‘Who’s Who’ of the biotechnology sector will meet in Heidelberg to experience an exciting programme and take advantage of the numerous networking opportunities. BioRN will support BioDeutschland e.V as coordinator and […]

GET IN TOUCH

Stay Updated with bioRN’s Newsletter

Sign up for our newsletter to discover more!
* required

BioRN (BioRN Network e.V. and BioRN Cluster Management GmbH) will use the information you provide on this form to be in touch with you and to provide updates and marketing. Please let us know all the ways you would like to hear from us:

You can update your subscription preferences or unsubscribe at any time. Just follow the unsubscribe or update link in the footer of automated emails you receive from us, or by contacting us at info@biorn.org. We will treat your information with respect. For more information about our privacy practices please visit our website: www.biorn.org. By clicking below, you agree that we may process your information in accordance with these terms.

We use Mailchimp as our marketing platform. By clicking below to subscribe, you acknowledge that your information will be transferred to Mailchimp for processing. Learn more about Mailchimp's privacy practices.

Intuit Mailchimp