Research
In a paper newly published in mAbs, Universität Stuttgart-, Technical University of Braunschweig-, and YUMAB GmbH-based authors reveal research results for novel antagonistic anti-EGFR antibodies that have potential to overcome resistance to current T-cell engagers against the same target. ABSTRACT Epidermal growth factor receptor (EGFR) is a validated therapeutic target in several human cancers harboring […]
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ariadne.ai SPATIAL Platform Enables Discovery of Novel Microglial Subpopulation in Human Alzheimer’s Disease Brain
Nature Neuroscience study identifies human plaque-associated microglia using deep learning-based cell segmentation
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Providing a cellular ‘all-clear’ signal to resume protein synthesis
Researchers’ newest technologies allow them to discover tiny protein that plays a big role in awakening dormant cells when it’s safe to resume normal operations Summary It’s a tough world for microbes. When resources grow limited and environments worsen, microbes have figured out ways to hunker down and go dormant until conditions improve. However, scientists […]
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Scientists uncover thousands of new proteins in ‘dark proteome’
An international consortium has found over 1,700 new proteins from noncoding DNA, many of which show potential as targets for cancer immunotherapy In a collaborative effort, scientists in the TransCODE consortium reveal more than 1,700 new proteins that could have implications for human diseases, including cancer. These tiny proteins were found in what’s called the […]
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The Plasticity of Malignant Brain Tumors as a Potential Therapeutic Approach: Sibylle Assmus Prize for Neuro-Oncology Awarded to Moritz Mall
The ability of cancer cells to change their identity makes tumors such as glioblastoma particularly aggressive and resistant to treatment. Moritz Mall, of the German Cancer Research Center (DKFZ) and the Hector Institute for Translational Brain Research (HITBR), is investigating how this plasticity can be specifically restricted. His approach focuses on genetic “guardians” that suppress […]
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Leukemia stem cells cause treatments to fail – Findings open new avenues to overcome resistance
Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM* Stem Cell Institute have deciphered a key mechanism that contributes to treatment failure in acute myeloid leukemia (AML). They show that there are not just one, but four different subtypes of leukemia stem cells. This diversity could explain why one of the most important […]
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What Really Helps People Quit Smoking
Whether people try to quit smoking depends heavily on public health policies in their respective countries – whether they are successful, however, depends primarily on their personal environment and behavior. This was the finding of researchers from the German Cancer Research Center (DKFZ) in an international study. The researchers analyzed data from over 50,000 smokers […]
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Lonza Announces Results of the 2026 Annual General Meeting – All Motions Proposed by Board of Directors Approved
Basel, Switzerland, 8 May 2026 – Today, Lonza Group Ltd held its Annual General Meeting (AGM), led by the Chair of the Board of Directors, Jean-Marc Huët. 62.58% of the share capital was represented at the AGM, with attending and represented shareholders collectively holding a total of 43,948,027 shares. All Board members standing for re-election were re-elected, each for a further term in office until the completion of the AGM 2027. The following Board members stood for re-election: Jean-Marc Huët, Juan […]
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A single swab is sufficient: Study paves the way for simplified tuberculosis diagnosis
Led by researchers from Heidelberg Faculty of Medicine at Heidelberg University and the University of California, San Francisco (USA), an international research team has evaluated a novel approach for the diagnosis of pulmonary tuberculosis. The method enables detection of Mycobacterium tuberculosis without laboratory infrastructure, within a markedly shorter time frame than conventional diagnostics, and using […]
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