March 20, 2026

Carl-Zeiss-Stiftung Funds Pioneering AI Project at the DKFZ

Carl-Zeiss-Stiftung Funds Pioneering AI Project at the DKFZ

How can artificial intelligence support medical imaging diagnostics in the future and significantly improve patient care? Researchers led by Lena Maier-Hein (German Cancer Research Center, DKFZ, and NCT Heidelberg) have developed an innovative concept to address this question. The Carl Zeiss-Stiftung is funding the MEDAL* project with a total of three million euros.

Experts and the general public alike expect artificial intelligence to bring improvements in many areas of medicine, particularly in diagnostic imaging. Potential applications range from early detection to diagnosis, from therapy assistance to Follow-up care. However, the development of such helpful AI solutions depends on the availability of relevant image data derived from CT or MRI imaging, pathology, and video documentation from surgical procedures. “Data drives research—current analyses show that research topics in AI are often selected based on what data is available, rather than on which clinical problems need to be solved most urgently,” says project leader Lena Maier-Hein, a medical informatics specialist at the DKFZ.

“Current test datasets often merely reflect simple routine tasks, such as recognizing or outlining specific structures. They therefore reveal little about how well modern AI systems understand complex medical contexts or can function reliably in new situations,” says Annika Reinke, senior scientist on the project.

This is exactly where MEDAL comes in: The project has the ambitious goal of building a globally unique collection of relevant clinical questions along with the corresponding image data. To this end, experts around the world are being called upon to participate in a large-scale crowdsourcing campaign and submit important clinical problems along with the associated multimodal data. A total prize fund of one million euros will be distributed among the contributors of the selected tasks.

With MEDAL, the researchers aim to create a kind of “final exam” that artificial general intelligence (AGI) systems in medical imaging must pass to demonstrate their clinical utility.

In Heidelberg, an international panel of experts comprising clinicians, data scientists, patient representatives, and AI researchers is currently being established under the leadership of Lena Maier Hein. The experts will select from among the submitted proposals those whose solutions are truly relevant to patients. The goal is to redirect the resources and creativity of the world’s brightest minds in the field of AI away from irrelevant or purely technical questions and toward the greatest clinical challenges of our time.

“We thank the Carl Zeiss-Stiftung for joining us on this unusual path. We hope to create a globally recognized standard with MEDAL to objectively measure the progress of medical AI,” says project leader Maier-Hein, adding: “Above all, however, MEDAL is intended to benefit patients by ensuring that future AI systems are specifically developed to address the most critical medical challenges.”

The funding from the Carl-Zeiss-Stiftung enables the implementation of this globally unique project and simultaneously strengthens Germany’s role in international AI research.

* MEDAL stands for “Medical Imaging AGI’s Last Exam”

Our latest News

discover more
Hummingbird Diagnostics to Present Blood-Based RNA Biomarker Data in Stage III Lung Cancer at ESMO 2026

Hummingbird Diagnostics to Present Blood-Based RNA Biomarker Data in Stage III Lung Cancer at ESMO 2026

More Information HEIDELBERG, Germany, September 30, 2026 – Hummingbird Diagnostics GmbH, a molecular diagnostics company specializing in blood-based small RNA analysis for precision oncology, today announced that data from a new collaborative study will be presented at the ESMO Congress 2026 in Madrid, Spain. Building on Hummingbird’s expertise in early cancer detection, the study explores […]

Greater Precision and Safety in Neurosurgical Procedures

Greater Precision and Safety in Neurosurgical Procedures

A new surgical system at the Department of Neurosurgery at Heidelberg University Hospital helps surgeons precisely plan procedures on the brain, spine, and skull base, monitor them during surgery, and perform them with millimeter precision. The “Robotic Surgery Suite,” which cost approximately 1.6 million euros, combines live imaging, digital navigation, and robotic assistance directly in […]

Mitochondrial Protein Complexes: A Single Amino Acid Can Jeopardize Their Stability

Mitochondrial Protein Complexes: A Single Amino Acid Can Jeopardize Their Stability

Scientists from Heidelberg and Freiburg identify the mechanism by which proteins assemble into stable complexes in mitochondria A tiny processing step has far-reaching consequences for mitochondrial function: The removal of a single amino acid determines whether new proteins can assemble into stable complexes within these cellular powerhouses. This process is carried out by a specific […]

GET IN TOUCH

Stay Updated with bioRN’s Newsletter

Sign up for our newsletter to discover more!
* required

BioRN (BioRN Network e.V. and BioRN Cluster Management GmbH) will use the information you provide on this form to be in touch with you and to provide updates and marketing. Please let us know all the ways you would like to hear from us:

You can update your subscription preferences or unsubscribe at any time. Just follow the unsubscribe or update link in the footer of automated emails you receive from us, or by contacting us at info@biorn.org. We will treat your information with respect. For more information about our privacy practices please visit our website: www.biorn.org. By clicking below, you agree that we may process your information in accordance with these terms.

We use Mailchimp as our marketing platform. By clicking below to subscribe, you acknowledge that your information will be transferred to Mailchimp for processing. Learn more about Mailchimp's privacy practices.

Intuit Mailchimp