Research

We are very proud to be a part of a joint, international effort to develop a genetically engineered mouse model (GEMM) for the understudied pediatric cancer, alveolar rhabdomyosarcoma (aRMS). This model, which has been deposited at JAX (strain 041178), will accelerate the development of living-saving therapies for children with aRMS. This model was developed as a […]

Computer simulations and Artificial Intelligence are the main pillars of the “SIMPLAIX” collaboration, initiated by the Heidelberg Institute for Theoretical Studies (HITS). Together with colleagues from Heidelberg University and Karlsruhe Institute of Technology (KIT), HITS researchers are addressing challenges in the simulation of biomolecules and molecular materials by pooling their expertise in multiscale computer simulation […]

A new study maps the organisation of immune and stromal cells in lymph nodes and shows how loss of this organisation affects prognosis in certain lymphomas Summary Researchers from EMBL Heidelberg, Heinrich Heine University Düsseldorf (HHU), and Düsseldorf University Hospital (UKD) have succeeded for the first time in mapping the organisation of immune and stromal […]

Meningiomas are the most common brain tumors. Until now, only two methods have generally been considered for treating them: surgery and radiation therapy. A research team in Heidelberg has now developed a potential new approach for effective systemic therapy. Its members from Heidelberg University’s Faculty of Medicine and Heidelberg University Hospital (UKHD) tested the effectiveness […]

An international team, including researchers from Heidelberg University’s Faculty of Medicine and Heidelberg University Hospital, has developed the PANGEA-SMM prognostic tool. This tool makes it possible to determine with greater accuracy than before whether a precancerous condition—known as “smoldering multiple myeloma”—is progressing and thus requires treatment. The free online tool for treatment teams is available […]

Full Text in German below. Strategische Investition in Deutschland: Roche weiht hochmodernes 90-Millionen-Euro-Distributionszentrum in Mannheim ein Mannheim, 23. März 2026 Mit einer Investition von 90 Millionen Euro stärkt Roche den Standort Mannheim als ein zentrales Drehkreuz im globalen Distributionsnetzwerk für Diagnostika des Unternehmens. Das neue Distributionszentrum für Europa umfasst eine Fläche von rund 16.300 Quadratmetern, […]

International research team under Heidelberg supervision examines role of NAC complex in essential process of protein folding In the earliest phase of creating human proteins, the protein complex NAC performs an essential task by starting the first steps towards folding proteins into their correct three-dimensional structures. This discovery was made by an international research team […]

For the first time, researchers have succeeded in mapping the organization of immune cells in human lymph nodes. The study was led by scientists from Heinrich Heine University Düsseldorf, Düsseldorf University Hospital, the German Cancer Research Center (DKFZ), the European Molecular Biology Laboratory (EMBL), and the Max Delbrück Center (MDC) in Berlin. They were able […]

In ovarian cancer, immunotherapies using checkpoint inhibitors have so far been effective in only a small number of patients. Researchers at the Helmholtz Institute for Translational Oncology (HI-TRON Mainz*) have now discovered that lipid metabolism processes in the tumor microenvironment play a decisive role in how well such therapies work. The findings open up new […]