
Research

Scientists at EMBL Heidelberg and University of Virginia School of Medicine have discovered a curious way in which cells adapt to starvation – a mechanism with potential cancer implications Summary What can stressed yeast teach us about fundamental processes in the cell? A lot, according to EMBL Heidelberg’s Mattei Team. The team studies, among other topics, […]
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Stronger together: miniature robots in convoy for endoscopic surgery
Miniature robots on the millimeter scale often lack the strength to transport instruments for endoscopic microsurgery through the body. Scientists at the German Cancer Research Center (DKFZ) are now combining several millimeter-sized TrainBots into one unit and equipping them with improved “feet”. For the first time, the DKFZ team was able to perform an electric […]
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Critical Pathway for rare brain tumor discovered
Choroid plexus tumors mainly affect toddlers under one year of age. Scientists at the German Cancer Research Center (DKFZ) have now been able to show that a permanently activated important signaling pathway of intracellular communication is responsible for the development of these rare brain tumors. Tumors of the choroid plexus develop as a result of […]
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Language model “UroBot“ surpasses the accuracy of experienced urologists
Scientists at the German Cancer Research Center (DKFZ), together with doctors from the Urological Clinic of the Mannheim University Hospital, have developed and successfully tested a chatbot based on artificial intelligence. “UroBot” was able to answer questions from the urology specialist examination with a high degree of accuracy, surpassing both other language models and the […]
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Better together: gut microbiome communities’ resilience to drugs
Bacteria that are sensitive to drugs can become resilient when part of communities, with the help of cross-protection strategies Summary Many human medications can directly inhibit the growth and alter the function of the bacteria that constitute our gut microbiome. EMBL Heidelberg researchers have now discovered that this effect is reduced when bacteria form communities. […]
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How Developmental Signals Can Contribute to Genomic Mosaicism
Heidelberg researchers identify biological mechanism that protects against, but can also trigger, errors in the genome Certain developmental signals shape not only the human embryo but also play a significant role in maintaining our genetic blueprints. They prevent alterations in the genome, known as mosaicism. An international research team led by scientists of the Centre […]
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Quality standards for looking into the tumor genome
Personalized medicine with individually tailored therapies is becoming more and more a reality in cancer. This requires a precise look into the genetic material of tumors, a molecular diagnostic tumor profile. A research group from the German Network for Personalized Medicine (DNPM) has recorded the quality standards according to which genome analyses are carried out […]
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Silencing in action: how cells ‘repress’ genomic remnants of ancient viruses
Researchers have identified key cellular control sites that regulate gene expression and prevent the activation of ‘cryptic’ genomic regions, including ancient viral sequences Summary For any organism to survive and thrive, its cells must strictly control which genes are active when and where. New research from EMBL Heidelberg’s Noh Group and their collaborators from EMBL […]
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Follow the cellular road
Scientists collaborate to customise top-of-the-line microscopy method with AI to better understand glioblastoma brain tumours Summary Imagine building a traffic surveillance camera that could detect trouble-making cells speeding around in your brain before their cellular gang could commit ‘crimes’. Most importantly, this camera could catch some of the biggest interlopers of all – cancer cells. […]
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